The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
about
The Casitas B lineage lymphoma (Cbl) mutant G306E enhances osteogenic differentiation in human mesenchymal stromal cells in part by decreased Cbl-mediated platelet-derived growth factor receptor alpha and fibroblast growth factor receptor 2 ubiquitiDown-regulation of ubiquitin ligase Cbl induced by twist haploinsufficiency in Saethre-Chotzen syndrome results in increased PI3K/Akt signaling and osteoblast proliferationSixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasiasDevelopment of a fluorescence polarization based high-throughput assay to identify Casitas B-lineage lymphoma RING domain regulatorsGene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells.c-Cbl-mediated degradation of TRAIL receptors is responsible for the development of the early phase of TRAIL resistance.The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptorsLow expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition.Proteolysis, the ubiquitin-proteasome system, and renal diseases.Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice.Molecular regulation of osteoclast activity.The serine/threonine kinase cyclin G-associated kinase regulates epidermal growth factor receptor signalingLoss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia.Integrative survival-based molecular profiling of human pancreatic cancer.Quantitative Proteomic Analysis of Escherichia coli Heat-Labile Toxin B Subunit (LTB) with Enterovirus 71 (EV71) Subunit VP1Cbl proteins in platelet activation.Targeting integrins to promote bone formation and repair.Molecular mechanisms of SH2- and PTB-domain-containing proteins in receptor tyrosine kinase signaling.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.FTY720 enhances TRAIL-mediated apoptosis by up-regulating DR5 and down-regulating Mcl-1 in cancer cells.Differences in growth promotion, drug response and intracellular protein trafficking of FLT3 mutants.c-CBL regulates melanoma proliferation, migration, invasion and the FAK-SRC-GRB2 nexus.
P2860
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P2860
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@ast
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@en
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@nl
type
label
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@ast
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@en
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@nl
prefLabel
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@ast
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@en
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@nl
P2093
P2860
P1476
The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
@en
P2093
P2860
P356
10.1126/STKE.2001.110.PE40
P577
2001-11-27T00:00:00Z