The critical role of epithelial-derived Act1 in IL-17- and IL-25-mediated pulmonary inflammation.
about
Structure and signalling in the IL-17 receptor familyThe roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunityIL-17 family: cytokines, receptors and signalingCrystal Structure of IL-17 Receptor B SEFIR DomainStructure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signalingThe IL-17 pathway as a major therapeutic target in autoimmune diseasesThe inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammationNADPH oxidase mediates synergistic effects of IL-17 and TNF-α on CXCL1 expression by epithelial cells after lung ischemia-reperfusion.Regulation of IL-9 expression by IL-25 signaling.The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo.The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signalingAllergen-induced airway remodeling is impaired in galectin-3-deficient miceSEF/IL-17R (SEFIR) is not enough: an extended SEFIR domain is required for il-17RA-mediated signal transduction.The adaptor protein CIKS/ACT1 is necessary for collagen-induced arthritis, and it contributes to the production of collagen-specific antibodyT-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthmaRegulation of serotonin-induced trafficking and migration of eosinophils.Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitisIL-17-induced NF-kappaB activation via CIKS/Act1: physiologic significance and signaling mechanismsInterleukin-17A promotes MUC5AC expression and goblet cell hyperplasia in nasal polyps via the Act1-mediated pathway.TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation.Collaborative interactions between type 2 innate lymphoid cells and antigen-specific CD4+ Th2 cells exacerbate murine allergic airway diseases with prominent eosinophiliaPlatelets from Asthmatic Individuals Show Less Reliance on GlycolysisRegulation of eosinophil trafficking by SWAP-70 and its role in allergic airway inflammationA CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability.CIKS/Act1-mediated signaling by IL-17 cytokines in context: implications for how a CIKS gene variant may predispose to psoriasis.Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population.Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathologyThe p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.Cutting Edge: IL-25 Targets Dendritic Cells To Attract IL-9-Producing T Cells in Acute Allergic Lung Inflammation.A Novel Nuclear Function for the Interleukin-17 Signaling Adaptor Protein Act1.TSG-6 protein is crucial for the development of pulmonary hyaluronan deposition, eosinophilia, and airway hyperresponsiveness in a murine model of asthma.CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction.IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner.HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilizationEpithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthmaGenetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency.Innate cells and T helper 2 cell immunity in airway inflammation.Epithelium: the interplay between innate and Th2 immunity.IL-17 signaling in host defense and inflammatory diseases.
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P2860
The critical role of epithelial-derived Act1 in IL-17- and IL-25-mediated pulmonary inflammation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The critical role of epithelia ...... diated pulmonary inflammation.
@ast
The critical role of epithelia ...... diated pulmonary inflammation.
@en
The critical role of epithelia ...... diated pulmonary inflammation.
@nl
type
label
The critical role of epithelia ...... diated pulmonary inflammation.
@ast
The critical role of epithelia ...... diated pulmonary inflammation.
@en
The critical role of epithelia ...... diated pulmonary inflammation.
@nl
prefLabel
The critical role of epithelia ...... diated pulmonary inflammation.
@ast
The critical role of epithelia ...... diated pulmonary inflammation.
@en
The critical role of epithelia ...... diated pulmonary inflammation.
@nl
P2093
P2860
P1476
The critical role of epithelia ...... diated pulmonary inflammation.
@en
P2093
Katarzyna Bulek
Mark Aronica
Shadi Swaidani
Weiguo Yin
Xiaoxia Li
Zizhen Kang
P2860
P304
P356
10.4049/JIMMUNOL.182.3.1631
P407
P577
2009-02-01T00:00:00Z