Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
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Immunohistochemical localization of phosphodiesterase 2A in multiple mammalian speciesCrystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine bindingPhosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment responseMolecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling UnitsCrystal structures of phosphodiesterases 4 and 5 in complex with inhibitor 3-isobutyl-1-methylxanthine suggest a conformation determinant of inhibitor selectivityStructural insight into substrate specificity of phosphodiesterase 10The Molecular Basis for Different Recognition of Substrates by Phosphodiesterase Families 4 and 10Conformational Variations of Both Phosphodiesterase-5 and Inhibitors Provide the Structural Basis for the Physiological Effects of Vardenafil and SildenafilStructural basis for the catalytic mechanism of human phosphodiesterase 9Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphologyPhosphodiesterase 7 inhibition preserves dopaminergic neurons in cellular and rodent models of Parkinson diseaseIdentification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi.A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design.Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells.PDE4 as a target in preterm labourMultiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7.Brain natriuretic peptide in pulmonary arterial hypertension: biomarker and potential therapeutic agentResveratrol and curcumin enhance pancreatic β-cell function by inhibiting phosphodiesterase activity.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Regulation and organization of adenylyl cyclases and cAMP.Central role of soluble adenylyl cyclase and cAMP in sperm physiology.Oocyte maturation: the coming of age of a germ cell.Effect of low dose exposure to the herbicide atrazine and its metabolite on cytochrome P450 aromatase and steroidogenic factor-1 mRNA levels in the brain of premetamorphic bullfrog tadpoles (Rana catesbeiana).Characterization of a catalytic ligand bridging metal ions in phosphodiesterases 4 and 5 by molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations.Two phosphodiesterases from ustilago maydis share structural and biochemical properties with non-fungal phosphodiesterasesInhibition of the tonic contraction in the treatment of erectile dysfunction.The PDE4 inhibitor rolipram prevents NF-kappaB binding activity and proinflammatory cytokine release in human chorionic cellsModulation of Leydig cell function by cyclic nucleotide phosphodiesterase 8A.Phosphodiesterase 7 inhibition induces dopaminergic neurogenesis in hemiparkinsonian rats.Targeting beta-cell cyclic 3'5' adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A review.Involvement of Src family of kinases and cAMP phosphodiesterase in the luteinizing hormone/chorionic gonadotropin receptor-mediated signaling in the corpus luteum of monkey.Granulocyte-colony stimulating factor activates JAK2/PI3K/PDE3B pathway to inhibit corticosterone synthesis in a neonatal hypoxic-ischemic brain injury rat model.Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatmentPhosphodiesterases and adrenal Cushing in mice and humans.PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women.The novel distribution of phosphodiesterase-4 subtypes within the rat retina.Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: two relevant therapeutic targets for neurological disorders.Clinical and molecular genetics of the phosphodiesterases (PDEs).TCF21 is related to testis growth and development in broiler chickens.
P2860
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P2860
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@ast
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@en
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@nl
type
label
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@ast
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@en
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@nl
prefLabel
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@ast
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@en
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
@nl
P2093
P1476
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling
@en
P2093
Carsten B Andersen
Marcello Filopanti
Marco Conti
S L Catherine Jin
P356
10.1016/S1043-2760(01)00523-9
P577
2002-01-01T00:00:00Z