Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
about
The genetically encoded tool set for investigating cAMP: more than the sum of its partsCyclic AMP dynamics in the pancreatic β-cellcAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.Cell physiology of cAMP sensor Epac.Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic SuccessesStriatal neurones have a specific ability to respond to phasic dopamine releaseCalcium-dependent increases in protein kinase-A activity in mouse retinal ganglion cells are mediated by multiple adenylate cyclasesAKAP79/150 interacts with AC8 and regulates Ca2+-dependent cAMP synthesis in pancreatic and neuronal systemsReal-time hyperspectral fluorescence imaging of pancreatic β-cell dynamics with the image mapping spectrometer.Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice.Imaging cytoplasmic cAMP in mouse brainstem neuronsSimultaneous live cell imaging using dual FRET sensors with a single excitation light.PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunctioncAMP mediators of pulsatile insulin secretion from glucose-stimulated single beta-cells.Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin.Regulation by Ca2+-signaling pathways of adenylyl cyclases.Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1.Intermingled cAMP, cGMP and calcium spatiotemporal dynamics in developing neuronal circuits.Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.Simultaneous quantitative live cell imaging of multiple FRET-based biosensors.Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit.Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart.The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs.An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.Dynamics of insulin secretion and the clinical implications for obesity and diabetesPhospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of LangerhansChronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase AP2Y6 receptor-mediated proinflammatory signaling in human bronchial epithelia.Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion.Glucose- and hormone-induced cAMP oscillations in α- and β-cells within intact pancreatic islets.SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretionGlucose Evokes Rapid Ca2+ and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells.Regulation of microRNA-375 by cAMP in pancreatic β-cells.Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational AnalysisBursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.Modeling of glucose-induced cAMP oscillations in pancreatic β cells: cAMP rocks when metabolism rollsThe A-kinase anchoring protein Yotiao facilitates complex formation between adenylyl cyclase type 9 and the IKs potassium channel in heart.Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells.Monitoring of cAMP synthesis and degradation in living cells.
P2860
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P2860
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
@ast
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
@en
type
label
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
@ast
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
@en
prefLabel
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
@ast
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
@en
P2093
P2860
P356
P1476
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
@en
P2093
George G Holz
Kajorn Kitiphongspattana
Kelly Kaihara
Luis R Landa
Mark Harbeck
Martin J Lohse
Michael W Roe
Oleg Chepurny
Oliver Graf
Viacheslav O Nikolaev
P2860
P304
31294-31302
P356
10.1074/JBC.M505657200
P407
P577
2005-06-29T00:00:00Z