Yeast DNA polymerase zeta is an efficient extender of primer ends opposite from 7,8-dihydro-8-Oxoguanine and O6-methylguanine
about
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerasesEukaryotic DNA polymerase ζDNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesionA fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dGA ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage.Reversal of PCNA ubiquitylation by Ubp10 in Saccharomyces cerevisiae.Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiaeGenetic instability in budding and fission yeast-sources and mechanismsDNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeTranslesion synthesis of 7,8-dihydro-8-oxo-2'-deoxyguanosine by DNA polymerase eta in vivo.Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrationsCharacterization of DNA with an 8-oxoguanine modification.Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast.Kinetic approaches to understanding the mechanisms of fidelity of the herpes simplex virus type 1 DNA polymeraseYeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair.CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae.Lesion bypass by S. cerevisiae Pol ζ alone.Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions.A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesisInhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.Balancing repair and tolerance of DNA damage caused by alkylating agentsDNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cellsDNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae.Proficient Replication of the Yeast Genome by a Viral DNA PolymeraseThe post-replication repair RAD18 and RAD6 genes are involved in the prevention of spontaneous mutations caused by 7,8-dihydro-8-oxoguanine in Saccharomyces cerevisiae.Translesion DNA synthesis and mutagenesis in eukaryotesOverexpression of Rev1 promotes the development of carcinogen-induced intestinal adenomas via accumulation of point mutation and suppression of apoptosis proportionally to the Rev1 expression level.Involvement of translesion synthesis DNA polymerases in DNA interstrand crosslink repairMinor Groove 3-Deaza-Adenosine Analogues: Synthesis and Bypass in Translesion DNA Synthesis.DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens.Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1.Generation, repair and replication of guanine oxidation products.A highly conserved Tyrosine residue of family B DNA polymerases contributes to dictate translesion synthesis past 8-oxo-7,8-dihydro-2'-deoxyguanosine.Unlike catalyzing error-free bypass of 8-oxodGuo, DNA polymerase λ is responsible for a significant part of Fapy·dG-induced G → T mutations in human cells.Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis.An archaeal family-B DNA polymerase variant able to replicate past DNA damage: occurrence of replicative and translesion synthesis polymerases within the B family.Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage.Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer.Non-bulky Lesions in Human DNA: the Ways of Formation, Repair, and Replication.
P2860
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P2860
Yeast DNA polymerase zeta is an efficient extender of primer ends opposite from 7,8-dihydro-8-Oxoguanine and O6-methylguanine
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@ast
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@en
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@nl
type
label
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@ast
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@en
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@nl
prefLabel
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@ast
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@en
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@nl
P2093
P2860
P1476
Yeast DNA polymerase zeta is a ...... xoguanine and O6-methylguanine
@en
P2093
Lajos Haracska
Louise Prakash
Satya Prakash
P2860
P304
P356
10.1128/MCB.23.4.1453-1459.2003
P407
P577
2003-02-01T00:00:00Z