about
In Vivo Analysis of Protein-Protein Interactions with Bioluminescence Resonance Energy Transfer (BRET): Progress and ProspectsUsing nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time.Target engagement and drug residence time can be observed in living cells with BRET.A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms.An ultrasensitive NanoLuc-based luminescence system for monitoring Plasmodium berghei throughout its life cycleNanoLuc: A Small Luciferase Is Brightening Up the Field of Bioluminescence.Fast and high resolution single-cell BRET imagingDetermination of GLUT1 Oligomerization Parameters using Bioluminescent Förster Resonance Energy Transfer.New paradigms in GPCR drug discovery.Fluorescence- and bioluminescence-based approaches to study GPCR ligand binding.G Protein-Coupled Receptor Heteromers.On the different experimental manifestations of two-state 'induced-fit' binding of drugs to their cellular targetsA novel BRET-based binding assay for interaction studies of relaxin family peptide receptor 3 with its ligands.Novel bioluminescent binding assays for interaction studies of protein/peptide hormones with their receptors.1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine.Monitoring Ligand-Activated Protein-Protein Interactions Using Bioluminescent Resonance Energy Transfer (BRET) Assay.GPCR Signaling and Trafficking: The Long and Short of It.Use of a new proximity assay (NanoBRET) to investigate the ligand-binding characteristics of three fluorescent ligands to the human β1-adrenoceptor expressed in HEK-293 cells.Dual Readout BRET/FRET Sensors for Measuring Intracellular Zinc.Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexesA monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines.Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase.Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells.A Non-imaging High Throughput Approach to Chemical Library Screening at the Unmodified Adenosine-A3 Receptor in Living Cells.Highly Efficient Intramolecular Electrochemiluminescence Energy Transfer for Ultrasensitive Bioanalysis of Aflatoxin M1.Using Biosensors to Study Free Fatty Acid Receptor Pharmacology and Function.Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y2 Receptor Based on AR-C118925.Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2.A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging.Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpressionReal-Time Ligand Binding of Fluorescent VEGF-A Isoforms that Discriminate between VEGFR2 and NRP1 in Living CellsVisualizing Ligand Binding to a GPCR In Vivo Using NanoBRET
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Application of BRET to monitor ligand binding to GPCRs.
@ast
Application of BRET to monitor ligand binding to GPCRs.
@en
Application of BRET to monitor ligand binding to GPCRs.
@nl
type
label
Application of BRET to monitor ligand binding to GPCRs.
@ast
Application of BRET to monitor ligand binding to GPCRs.
@en
Application of BRET to monitor ligand binding to GPCRs.
@nl
prefLabel
Application of BRET to monitor ligand binding to GPCRs.
@ast
Application of BRET to monitor ligand binding to GPCRs.
@en
Application of BRET to monitor ligand binding to GPCRs.
@nl
P2093
P2860
P356
P1433
P1476
Application of BRET to monitor ligand binding to GPCRs.
@en
P2093
Amanda J Wheal
Elizabeth K M Johnstone
Joëlle Goulding
Keith V Wood
Kevin D G Pfleger
Matthew B Robers
Thomas Machleidt
P2860
P2888
P304
P356
10.1038/NMETH.3398
P577
2015-06-01T00:00:00Z
P6179
1041046670