Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics.
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Basic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor HeteromerizationThe evolving small-molecule fluorescent-conjugate toolbox for Class A GPCRsFluorescent approaches for understanding interactions of ligands with G protein coupled receptorsA new mechanism of allostery in a G protein-coupled receptor dimerActivation biosensor for G protein-coupled receptors: a FRET-based m1 muscarinic activation sensor that regulates G(q)Fragment screening at adenosine-A(3) receptors in living cells using a fluorescence-based binding assay.Application of BRET to monitor ligand binding to GPCRs.Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: molecular modeling and experimental validation.Click modification in the N6 region of A3 adenosine receptor-selective carbocyclic nucleosides for dendrimeric tethering that preserves pharmacophore recognition.Lighting up G protein-coupled purinergic receptors with engineered fluorescent ligands.Fluorescent ligands for adenosine receptors.The prevalence, maintenance, and relevance of G protein-coupled receptor oligomerizationFluorescence- and bioluminescence-based approaches to study GPCR ligand binding.G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives.Approaches for probing allosteric interactions at 7 transmembrane spanning receptors.Allosteric interactions at adenosine A(1) and A(3) receptors: new insights into the role of small molecules and receptor dimerization.Biophysical Detection of Diversity and Bias in GPCR Function.Quantitative analysis of receptor allosterism and its implication for drug discovery.Structural Probing and Molecular Modeling of the A₃ Adenosine Receptor: A Focus on Agonist Binding.Investigation of GPCR allosterism and dimerization in single living cells using fluorescent ligands.Contributions of fluorescence techniques to understanding G protein-coupled receptor dimerisation.A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy.Use of a new proximity assay (NanoBRET) to investigate the ligand-binding characteristics of three fluorescent ligands to the human β1-adrenoceptor expressed in HEK-293 cells.Hints on the Lateralization of Dopamine Binding to D1 Receptors in Rat Striatum.Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexesNegative cooperativity across β1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation.Kinetic analysis of antagonist-occupied adenosine-A3 receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism.Fluorescent ligands for G protein-coupled receptors: illuminating receptor-ligand interactions for drug discovery.Spatial Intensity Distribution Analysis: Studies of G Protein-Coupled Receptor Oligomerisation.Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells.A kinetic view of GPCR allostery and biased agonism.Adenosine A2A receptor ligand recognition and signaling is blocked by A2B receptors.Implications for human odor sensing revealed from the statistics of odorant-receptor interactions.
P2860
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P2860
Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Allosteric interactions across ...... -cell ligand-binding kinetics.
@ast
Allosteric interactions across ...... -cell ligand-binding kinetics.
@en
type
label
Allosteric interactions across ...... -cell ligand-binding kinetics.
@ast
Allosteric interactions across ...... -cell ligand-binding kinetics.
@en
prefLabel
Allosteric interactions across ...... -cell ligand-binding kinetics.
@ast
Allosteric interactions across ...... -cell ligand-binding kinetics.
@en
P2860
P50
P356
P1433
P1476
Allosteric interactions across ...... -cell ligand-binding kinetics.
@en
P2093
Lauren T May
Lloyd J Bridge
P2860
P304
P356
10.1096/FJ.11-186296
P407
P577
2011-06-29T00:00:00Z