The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells.
about
Molecular cloning of the human CTP synthetase gene by functional complementation with purified human metaphase chromosomesCyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repairThe clinically relevant pharmacogenomic changes in acute myelogenous leukemiaDNA replication fidelity and cancerApoptosis of haematopoietic cells upon thymidylate synthase inhibition is independent of p53 accumulation and CD95-CD95 ligand interactionThe antiretrovirus drug 3'-azido-3'-deoxythymidine increases the retrovirus mutation rateInitiation of genome instability and preneoplastic processes through loss of Fhit expressionManipulation of cell cycle progression can counteract the apparent loss of correction frequency following oligonucleotide-directed gene repair.Apoptosis induced by replication inhibitors in Chk1-depleted cells is dependent upon the helicase cofactor Cdc45.Deoxyribonucleoside triphosphate pool imbalances in vivo are associated with an increased retroviral mutation ratePreclinical aspects of lamivudine and famciclovir against hepatitis B virus.Human immunodeficiency virus type 1 DNA sequences genetically damaged by hypermutation are often abundant in patient peripheral blood mononuclear cells and may be generated during near-simultaneous infection and activation of CD4(+) T cells.Valine, not methionine, is amino acid 106 in human cytosolic thymidine kinase (TK1). Impact on oligomerization, stability, and kinetic properties.Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stabilitySimulating pseudogene evolution in vitro: determining the true number of mutations in a lineage.Nucleotide metabolism, oncogene-induced senescence and cancer.A mammalian-like DNA damage response of fission yeast to nucleoside analogsProblems related to resistance to cytarabine in acute myeloid leukemia.Actinomycin D induces high-level resistance to thymidine analogs in replication of human immunodeficiency virus type 1 by interfering with host cell thymidine kinase expression.Defining a genotoxic profile with mouse embryonic stem cellsThe essentiality of folate for the maintenance of deoxynucleotide precursor pools, DNA synthesis, and cell cycle progression in PHA-stimulated lymphocytes.Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferationG-->A hypermutation of the human immunodeficiency virus type 1 genome: evidence for dCTP pool imbalance during reverse transcription.Mycoplasmas and cancer: focus on nucleoside metabolismInduction of mutations in Drosophila melanogaster gypsy retroelements by modulation of intracellular deoxynucleoside triphosphate pools in vivoHypermutagenesis of RNA using human immunodeficiency virus type 1 reverse transcriptase and biased dNTP concentrations.Association of Somatic Mutations of ADAMTS Genes With Chemotherapy Sensitivity and Survival in High-Grade Serous Ovarian CarcinomaMammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cellsExtreme dNTP pool changes and hypermutability in dcd ndk strains.Chromosomal location and structural organization of the human deoxycytidylate deaminase gene.Temperature-sensitive DNA mutant of Chinese hamster ovary cells with a thermolabile ribonucleotide reductase activity.Methotrexate induces differentiation of human keratinocytes.Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.Hypermutagenic PCR involving all four transitions and a sizeable proportion of transversions.Heterozygous colon cancer-associated mutations of SAMHD1 have functional significanceRRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients.Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis.Genetic factors influencing cytarabine therapy.Mitochondrial decay in ageing: 'Qi-invigorating' schisandrin B as a hormetic agent for mitigating age-related diseases.The role of thymidine kinase in cancer diseases.
P2860
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P2860
The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells.
description
1989 nî lūn-bûn
@nan
1989 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
The molecular basis of mutatio ...... imbalances in mammalian cells.
@ast
The molecular basis of mutatio ...... imbalances in mammalian cells.
@en
The molecular basis of mutatio ...... imbalances in mammalian cells.
@nl
type
label
The molecular basis of mutatio ...... imbalances in mammalian cells.
@ast
The molecular basis of mutatio ...... imbalances in mammalian cells.
@en
The molecular basis of mutatio ...... imbalances in mammalian cells.
@nl
prefLabel
The molecular basis of mutatio ...... imbalances in mammalian cells.
@ast
The molecular basis of mutatio ...... imbalances in mammalian cells.
@en
The molecular basis of mutatio ...... imbalances in mammalian cells.
@nl
P1476
The molecular basis of mutatio ...... imbalances in mammalian cells.
@en
P2093
P304
P356
10.1016/0014-4827(89)90090-6
P407
P577
1989-04-01T00:00:00Z