Deoxyribonucleoside triphosphate pool imbalances in vivo are associated with an increased retroviral mutation rate
about
APOBEC3G contributes to HIV-1 variation through sublethal mutagenesisGenetic Drift, Purifying Selection and Vector Genotype Shape Dengue Virus Intra-host Genetic Diversity in MosquitoesHIV-1 reverse transcriptionVariation in RNA virus mutation rates across host cellsExtremely High Mutation Rate of HIV-1 In VivoInfluence of reverse transcriptase variants, drugs, and Vpr on human immunodeficiency virus type 1 mutant frequencies.3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1.Cloning and characterization of full-length mouse thymidine kinase 2: the N-terminal sequence directs import of the precursor protein into mitochondria.Influence of vector design and host cell on the mechanism of recombination and emergence of mutant subpopulations of replicating retroviral vectors.Deciphering Evolutionary Mechanisms Between Mutualistic and Pathogenic SymbiosesStructural determinants of murine leukemia virus reverse transcriptase that affect the frequency of template switchingHuman immunodeficiency virus type 1 DNA sequences genetically damaged by hypermutation are often abundant in patient peripheral blood mononuclear cells and may be generated during near-simultaneous infection and activation of CD4(+) T cells.Dynamic copy choice: steady state between murine leukemia virus polymerase and polymerase-dependent RNase H activity determines frequency of in vivo template switching.The level of APOBEC3G (hA3G)-related G-to-A mutations does not correlate with viral load in HIV type 1-infected individuals.In vivo HIV-1 hypermutation and viral loads among antiretroviral-naive Brazilian patients.Zinc finger domain of murine leukemia virus nucleocapsid protein enhances the rate of viral DNA synthesis in vivo.A small-molecule blocking ribonucleotide reductase holoenzyme formation inhibits cancer cell growth and overcomes drug resistance5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.Mechanisms and factors that influence high frequency retroviral recombinationCell cycle status of CD34(+) hemopoietic stem cells determines lentiviral integration in actively transcribed and development-related genes.Alternative divalent cations (Zn²⁺, Co²⁺, and Mn²⁺) are not mutagenic at conditions optimal for HIV-1 reverse transcriptase activity.p53 mediates senescence-like arrest induced by chronic replicational stressSubunit-selective mutational analysis and tissue culture evaluations of the interactions of the E138K and M184I mutations in HIV-1 reverse transcriptase.Rad53 is essential for a mitochondrial DNA inheritance checkpoint regulating G1 to S progression.Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency.Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1Mutation rates and intrinsic fidelity of retroviral reverse transcriptases.5,6-Dihydro-5-aza-2'-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors.Variation of HIV-1 mutation spectra among cell types.Back to the future: revisiting HIV-1 lethal mutagenesis.Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells.Altering the intracellular environment increases the frequency of tandem repeat deletion during Moloney murine leukemia virus reverse transcription.Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequenciesPseudodiploid genome organization AIDS full-length human immunodeficiency virus type 1 DNA synthesis.Increased G-->A transition frequencies displayed by primer grip mutants of human immunodeficiency virus type 1 reverse transcriptaseResolution of Specific Nucleotide Mismatches by Wild-Type and AZT-Resistant Reverse Transcriptases during HIV-1 Replication.Activation of the prereplication complex is blocked by mimosine through reactive oxygen species-activated ataxia telangiectasia mutated (ATM) protein without DNA damage.
P2860
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P2860
Deoxyribonucleoside triphosphate pool imbalances in vivo are associated with an increased retroviral mutation rate
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Deoxyribonucleoside triphospha ...... eased retroviral mutation rate
@ast
Deoxyribonucleoside triphospha ...... eased retroviral mutation rate
@en
type
label
Deoxyribonucleoside triphospha ...... eased retroviral mutation rate
@ast
Deoxyribonucleoside triphospha ...... eased retroviral mutation rate
@en
prefLabel
Deoxyribonucleoside triphospha ...... eased retroviral mutation rate
@ast
Deoxyribonucleoside triphospha ...... eased retroviral mutation rate
@en
P2860
P1433
P1476
Deoxyribonucleoside triphospha ...... eased retroviral mutation rate
@en
P2093
J G Julias
P2860
P304
P577
1998-10-01T00:00:00Z