Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.
about
Promiscuous DNA synthesis by human DNA polymerase θMechanism of microhomology-mediated end-joining promoted by human DNA polymerase θDNA polymerase θ (POLQ), double-strand break repair, and cancerDNA Polymerase θ: A Unique Multifunctional End-Joining MachineMicrohomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?Microhomology-mediated end joining: new players join the teamA transposon-derived DNA polymerase from Entamoeba histolytica displays intrinsic strand displacement, processivity and lesion bypassMechanism of suppression of chromosomal instability by DNA polymerase POLQHow a homolog of high-fidelity replicases conducts mutagenic DNA synthesisA role for DNA polymerase θ in promoting replication through oxidative DNA lesion, thymine glycol, in human cells.Translesion DNA polymerasesA DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study.The biochemistry and fidelity of synthesis by the apicoplast genome replication DNA polymerase Pfprex from the malaria parasite Plasmodium falciparumHuman DNA polymerase θ grasps the primer terminus to mediate DNA repairSingle-nucleotide polymorphisms in DNA bypass polymerase genes and association with breast cancer and breast cancer subtypes among African Americans and Whites.DNA polymerase from temperate phage Bam35 is endowed with processive polymerization and abasic sites translesion synthesis capacity.Linking DNA polymerase theta structure and function in health and diseaseDNA polymerase POLQ and cellular defense against DNA damage.Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joiningDNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotidesReplication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine.Mechanisms of base substitution mutagenesis in cancer genomes.Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival.A role for DNA polymerase θ in the timing of DNA replication.Eukaryotic DNA Polymerases in Homologous Recombination.Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells.Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.Modification of 3' Terminal Ends of DNA and RNA Using DNA Polymerase θ Terminal Transferase Activity.A putative Leishmania DNA polymerase theta protects the parasite against oxidative damage.Expression and Structural Analyses of Human DNA Polymerase θ (POLQ).Plant organellar DNA polymerases are replicative and translesion DNA synthesis polymerases.The A-Rule and Deletion Formation During Abasic and Oxidized Abasic Site Bypass by DNA Polymerase θ.Polymerase θ-helicase efficiently unwinds DNA and RNA-DNA hybrids
P2860
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P2860
Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Lesion bypass activity of DNA ...... ds on unique sequence inserts.
@ast
Lesion bypass activity of DNA ...... ds on unique sequence inserts.
@en
Lesion bypass activity of DNA polymerase θ
@nl
type
label
Lesion bypass activity of DNA ...... ds on unique sequence inserts.
@ast
Lesion bypass activity of DNA ...... ds on unique sequence inserts.
@en
Lesion bypass activity of DNA polymerase θ
@nl
prefLabel
Lesion bypass activity of DNA ...... ds on unique sequence inserts.
@ast
Lesion bypass activity of DNA ...... ds on unique sequence inserts.
@en
Lesion bypass activity of DNA polymerase θ
@nl
P2860
P50
P1476
Lesion bypass activity of DNA ...... nds on unique sequence inserts
@en
P2093
Matthew Hogg
Mineaki Seki
P2860
P304
P356
10.1016/J.JMB.2010.10.041
P407
P577
2010-11-02T00:00:00Z