Genome mining in Streptomyces coelicolor: molecular cloning and characterization of a new sesquiterpene synthase
about
Identification of sesquiterpene synthases from Nostoc punctiforme PCC 73102 and Nostoc sp. strain PCC 7120Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2)Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active siteDynamic behavior of rearranging carbocations - implications for terpene biosynthesisStructure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates ,Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi -Isozizaene SynthaseBiochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolorExperimental and Theoretical Studies on Corvol Ether Biosynthesis.Mechanistic investigations on six bacterial terpene cyclasesNatural products version 2.0: connecting genes to molecules.Terpenoids are widespread in actinomycetes: a correlation of secondary metabolism and genome data.Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseusSesquiterpene synthases: passive catalysts or active players?The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2Genomic basis for natural product biosynthetic diversity in the actinomycetesIdentification and functional analysis of genes controlling biosynthesis of 2-methylisoborneolVolatile terpenes from actinomycetes: a biosynthetic study correlating chemical analyses to genome data.Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerusIsoprenoids in three-dimensional space: the stereochemistry of terpene biosynthesis.Exploration and mining of the bacterial terpenome.Antimicrobials, drug discovery, and genome mining.Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways.Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways.Capturing volatile natural products by mass spectrometry.Discovery of microbial natural products by activation of silent biosynthetic gene clusters.Bacterial terpene cyclases.Conformational Analysis, Thermal Rearrangement, and EI-MS Fragmentation Mechanism of (1(10)E,4E,6S,7R)-Germacradien-6-ol by (13)C-Labeling Experiments.Structural and Chemical Biology of Terpenoid Cyclases.Volatiles from nineteen recently genome sequenced actinomycetes.Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi-isozizaene albaflavenone biosynthesis and isolation of a new oxidized epi-isozizaene metabolite.Trinuclear Metal Clusters in Catalysis by Terpenoid Synthases.High-throughput screening for terpene-synthase-cyclization activity and directed evolution of a terpene synthase.Integrated metabolomics approach facilitates discovery of an unpredicted natural product suite from Streptomyces coelicolor M145.Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor. Mechanism and stereochemistry of the enzymatic formation of epi-isozizaene.Rapid chemical characterization of bacterial terpene synthases.Modulation of inherent dynamical tendencies of the bisabolyl cation via preorganization in epi-isozizaene synthase.Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.Mechanisms of the Diterpene Cyclases β-Pinacene Synthase from Dictyostelium discoideum and Hydropyrene Synthase from Streptomyces clavuligerus.Divalent transition-metal-ion stress induces prodigiosin biosynthesis in Streptomyces coelicolor M145: formation of coeligiosins.Identification of a sesquiterpene synthase-3-hydroxy-3-methylglutaryl-CoA synthase fusion protein responsible for hirsutene biosynthesis in Stereum hirsutum.
P2860
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P2860
Genome mining in Streptomyces coelicolor: molecular cloning and characterization of a new sesquiterpene synthase
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@ast
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@en
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@nl
type
label
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@ast
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@en
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@nl
prefLabel
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@ast
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@en
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@nl
P2093
P2860
P356
P1476
Genome mining in Streptomyces ...... f a new sesquiterpene synthase
@en
P2093
David E Cane
Russell Hopson
P2860
P304
P356
10.1021/JA061292S
P407
P577
2006-05-01T00:00:00Z