Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
about
Transcription factor GATA-1 and Down syndrome leukemogenesisETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cellsUnderstanding the basis for Down syndrome phenotypes.Treatment and prognostic impact of transient leukemia in neonates with Down syndromeThe OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.Distinctive hematological abnormalities in East Asian neonates and children with Down syndrome.The prenatal origins of cancerA novel role of CKIP-1 in promoting megakaryocytic differentiationA unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder.Down syndrome and malignancies: a unique clinical relationship: a paper from the 2008 william beaumont hospital symposium on molecular pathologyConcise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cellsOrigins of leukaemia in children with Down syndrome.Vitamin supplement use among children with Down's syndrome and risk of leukaemia: a Children's Oncology Group (COG) studyMiR-1246: a new link of the p53 family with cancer and Down syndrome.Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia.Myeloid Proliferations Associated with Down Syndrome.Haematology of Down syndromeErythroid and megakaryocytic transformation.Constitutional aneuploidy and cancer predisposition.Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndromeGATA1 mutations in a cohort of Malaysian children with Down syndrome-associated myeloid disorderDevelopment of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes.Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome.GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.Unique clinical and biological features of leukemia in Down syndrome children.Leukocytosis in an infant with Down syndrome.Haematopoietic development and leukaemia in Down syndrome.Acute megakaryoblastic leukemia with acquired trisomy 21 and GATA1 mutations in phenotypically normal children.Fetal liver stromal cells support blast growth in transient abnormal myelopoiesis in Down syndrome through GM-CSF.Distinct GATA1 Point Mutations in Monozygotic Twins With Down Syndrome and Transient Abnormal Myelopoiesis From a Triplet Pregnancy: A Case Report and Review of Literature.Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cellsThe GATA1s isoform is normally down-regulated during terminal haematopoietic differentiation and over-expression leads to failure to repress MYB, CCND2 and SKI during erythroid differentiation of K562 cells.Transient Myeloproliferative Disorder and Down Syndrome: Is there a link?The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas.Blast cell deficiency of CD11a as a marker of acute megakaryoblastic leukemia and transient myeloproliferative disease in children with and without Down syndrome.Transient abnormal myelopoiesis/acute megakaryoblastic leukemia diagnosed in the placenta of a stillborn Down syndrome fetus with targeted next-generation sequencing.Extensive placental choriovascular infiltration by maturing myeloid cells in down syndrome-associated transient abnormal myelopoiesis.Functional differences between myeloid leukemia-initiating and transient leukemia cells in Down's syndrome.Liver disease is frequently observed in Down syndrome patients with transient abnormal myelopoiesis.
P2860
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P2860
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
description
2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
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2003 թվականի մարտին հրատարակված գիտական հոդված
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2003年の論文
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2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年學術文章
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name
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@ast
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@en
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@nl
type
label
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@ast
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@en
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@nl
prefLabel
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@ast
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@en
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@nl
P2860
P1476
Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.
@en
P2093
Alvin Zipursky
P2860
P304
P356
10.1046/J.1365-2141.2003.04229.X
P407
P577
2003-03-01T00:00:00Z