Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease.

Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease.

http://www.wikidata.org/entity/Q34532864

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HSV-1 and Alzheimer's disease: more than a hypothesis.The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer-treated hippocampal neurons Long-term dantrolene treatment reduced intraneuronal amyloid in aged Alzheimer triple transgenic mice Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Differential rescue of spatial memory deficits in aged rats by L-type voltage-dependent calcium channel and ryanodine receptor antagonism.A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome Altered brain protein expression profiles are associated with molecular neurological dysfunction in the PKU mouse model.Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease.Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop.Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease Neuronal calcium signaling: function and dysfunction.Network-wide dysregulation of calcium homeostasis in Alzheimer's disease.Ryanodine receptors: physiological function and deregulation in Alzheimer disease.Dantrolene, a treatment for Alzheimer disease?Disturbed calcium signaling in spinocerebellar ataxias and Alzheimer's disease.Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained.Calcium's role as nuanced modulator of cellular physiology in the brain.Dysregulation of neuronal calcium homeostasis in Alzheimer's disease - A therapeutic opportunity?Emerging pathways driving early synaptic pathology in Alzheimer's disease.Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells.Calcium signaling and molecular mechanisms underlying neurodegenerative diseases.Ca2+ Release Channels Join the 'Resolution Revolution'.Modulating ryanodine receptors with dantrolene attenuates neuronopathic phenotype in Gaucher disease mice.Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer's disease mice.Ryanodine receptors: dual contribution to Alzheimer disease?Molecular and functional identification of a mitochondrial ryanodine receptor in neurons.Can the calcium hypothesis explain synaptic loss in Alzheimer's disease?Protective effects of β-sheet breaker α/β-hybrid peptide against amyloid β-induced neuronal apoptosis in vitro.Calcium Dysregulation in Alzheimer's Disease: A Target for New Drug Development.Interactions of Mitochondria/Metabolism and Calcium Regulation in Alzheimer's Disease: A Calcinist Point of View.Intracellular Ca2+ stores control in vivo neuronal hyperactivity in a mouse model of Alzheimer's disease.Early Alterations of Hippocampal Neuronal Firing Induced by Abeta42.An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging.On the Role of Store-Operated Calcium Entry in Acute and Chronic Neurodegenerative Diseases.Ryanodine Receptors in Autophagy: Implications for Neurodegenerative Diseases?Computer-Aided Multi-Target Management of Emergent Alzheimer's Disease.

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Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease.

http://www.wikidata.org/entity/Q34532864

description

2012 nî lūn-bûn

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2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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JOURNAL.PONE.0052056

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Stabilizing ER Ca2+ channel fu ...... ategy for Alzheimer's disease.

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Benjamin G Cameransi

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Clark Briggs

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Corinne Schneider

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Grace E Stutzmann

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Ivan Goussakov

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Jaime Wicks

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Jill C Richardson

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Joyce Kim

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Megan B Miller

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Shreaya Chakroborty

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P2860

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.

Abeta deposition and related pathology in an APP x PS1 transgenic mouse model of Alzheimer's disease.

Calcium signaling and amyloid toxicity in Alzheimer disease.

Calcium ions promote formation of amyloid β-peptide (1-40) oligomers causally implicated in neuronal toxicity of Alzheimer's disease.

Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons.

Role of presenilins in neuronal calcium homeostasis

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10.1371/JOURNAL.PONE.0052056

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12

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2012-12-21T00:00:00Z

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235437709

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23284867

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Alzheimer's disease

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3528716

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