Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans. - Wikidata - wikimedia - TriplyDB

Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans.

Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans.

http://www.wikidata.org/entity/Q34534117

about

Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets Crossing the Vascular Wall: Common and Unique Mechanisms Exploited by Different Leukocyte Subsets during Extravasation Memory T Cell Migration Dendritic cell subsets in type 1 diabetes: friend or foe?Cognate antigen directs CD8+ T cell migration to vascularized transplants Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation.An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ.Insulin as a key autoantigen in the development of type 1 diabetes The central role of antigen presentation in islets of Langerhans in autoimmune diabetes Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response.Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice.Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse Antigen recognition in the islets changes with progression of autoimmune islet infiltration.High-throughput sequencing of islet-infiltrating memory CD4+ T cells reveals a similar pattern of TCR Vβ usage in prediabetic and diabetic NOD mice Population dynamics of islet-infiltrating cells in autoimmune diabetes.T cell-driven initiation and propagation of autoimmune diabetes The Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases.DCIR2+ cDC2 DCs and Zbtb32 Restore CD4+ T-Cell Tolerance and Inhibit Diabetes Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells.Metagenomics and personalized medicine.Antigen presentation events during the initiation of autoimmune diabetes in the NOD mouse Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function The role of islet antigen presenting cells and the presentation of insulin in the initiation of autoimmune diabetes in the NOD mouse.Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease.Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes.Anti-coreceptor therapy drives selective T cell egress by suppressing inflammation-dependent chemotactic cues.CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes.Antigen presentation events in autoimmune diabetes.Peripheral tolerance and autoimmunity: lessons from in vivo imaging.Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation.Neutralization Versus Reinforcement of Proinflammatory Cytokines to Arrest Autoimmunity in Type 1 Diabetes.CD8+ Effector T Cell Migration to Pancreatic Islet Grafts Is Dependent on Cognate Antigen Presentation by Donor Graft Cells Transplant rejection and paradigms lost.Gatekeeper role of brain antigen-presenting CD11c+ cells in neuroinflammation.Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice.The islet-resident macrophage is in an inflammatory state and senses microbial products in blood.Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex.CD4+ T Helper Cells Play a Key Role in Maintaining Diabetogenic CD8+ T Cell Function in the Pancreas.The resident macrophages in murine pancreatic islets are constantly probing their local environment, capturing beta cell granules and blood particles.

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Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans.

http://www.wikidata.org/entity/Q34534117

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Cellular and molecular events ...... cells to islets of Langerhans.

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Cellular and molecular events ...... cells to islets of Langerhans.

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Cellular and molecular events ...... cells to islets of Langerhans.

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type

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Cellular and molecular events ...... cells to islets of Langerhans.

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Cellular and molecular events ...... cells to islets of Langerhans.

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Cellular and molecular events ...... cells to islets of Langerhans.

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Cellular and molecular events ...... cells to islets of Langerhans.

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Cellular and molecular events ...... cells to islets of Langerhans.

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Cellular and molecular events ...... cells to islets of Langerhans.

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PNAS.1018973108

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Cellular and molecular events ...... cells to islets of Langerhans.

@en

P2093

Boris Calderon

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Javier A Carrero

http://www.w3.org/2001/XMLSchema#string

Mark J Miller

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P2860

Visualizing dendritic cell networks in vivo

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules

Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement.

Autoimmune T cell responses in the central nervous system

Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice

In vivo activation of antigen-specific CD4 T cells.

Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response.

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes.

Three or more routes for leukocyte migration into the central nervous system.

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