CD28-mediated co-stimulation: a quantitative support for TCR signalling.
about
A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28Adoptive immunotherapy for cancer: building on successT cell activationPhosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell ActivationDisturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus ErythematosusCancer immunotherapy for pancreatic cancer utilizing α-gal epitope/natural anti-Gal antibody reactionVaccines for pancreatic cancerCTLA-4 blockade in tumor models: an overview of preclinical and translational researchThe role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosisRole of microglia in CNS autoimmunityT cell ageing: effects of age on development, survival & functionSignaling signatures and functional properties of anti-human CD28 superagonistic antibodiesUnraveling the Role of Allo-Antibodies and Transplant InjuryTargeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potentialCD28 and CTLA-4 coreceptor expression and signal transductionCo-stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamilySignaling by the phosphoinositide 3-kinase family in immune cellsControlling NF-kappaB activation in T cells by costimulatory receptorsCrystal structure of a soluble CD28-Fab complexApplication of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteinsIpilimumab: from preclinical development to future clinical perspectives in melanoma.MiR-150 impairs inflammatory cytokine production by targeting ARRB-2 after blocking CD28/B7 costimulatory pathway.Tumor masses support naive T cell infiltration, activation, and differentiation into effectorsSpatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation.Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal.Signals and sequences that control CD28 localization to the central region of the immunological synapse.PATHLOGIC-S: a scalable Boolean framework for modelling cellular signallingPhase I clinical trial of fibronectin CH296-stimulated T cell therapy in patients with advanced cancer.NSOM/QD-based direct visualization of CD3-induced and CD28-enhanced nanospatial coclustering of TCR and coreceptor in nanodomains in T cell activation.Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activityCD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production.IL-21 preferentially enhances IL-15-mediated homeostatic proliferation of human CD28+ CD8 memory T cells throughout the adult age span.Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligaseOrganization of proximal signal initiation at the TCR:CD3 complex.Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters.Id1 expression promotes T regulatory cell differentiation by facilitating TCR costimulation.Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cellsImmunosuppressive effects of erythropoietin on human alloreactive T cellsAbrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice.Clinical outcome in patients with acute coronary syndrome and outward remodeling is associated with a predominant inflammatory response.
P2860
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P2860
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@ast
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@en
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@nl
type
label
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@ast
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@en
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@nl
prefLabel
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@ast
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@en
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@nl
P356
P1476
CD28-mediated co-stimulation: a quantitative support for TCR signalling.
@en
P2093
Frédérique Michel
Oreste Acuto
P2888
P304
P356
10.1038/NRI1248
P577
2003-12-01T00:00:00Z
P6179
1001204816