CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production.
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Balancing Immune Protection and Immune Pathology by CD8(+) T-Cell Responses to Influenza InfectionCurrent status of immunotherapyImproving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer VaccinationTargeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potentialStimulating CD27 to quantitatively and qualitatively shape adaptive immunity to cancer.CD70 and IFN-1 selectively induce eomesodermin or T-bet and synergize to promote CD8+ T-cell responses.Dual function of CD70 in viral infection: modulator of early cytokine responses and activator of adaptive responses.Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help.Re-adapting T cells for cancer therapy: from mouse models to clinical trials.New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function.The IL-2 defect in systemic lupus erythematosus disease has an expansive effect on host immunityEarly events governing memory CD8+ T-cell differentiation.Regulation of tissue-dependent differences in CD8+ T cell apoptosis during viral infection.Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2.Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T cell populations.Long term recall of memory CD8 T cells in mice to first and third generation smallpox vaccines.Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathwayCo-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy.OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.An alternative signal 3: CD8⁺ T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling.CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremiaMemory programming in CD8(+) T-cell differentiation is intrinsic and is not determined by CD4 help.Characterization of the human T cell response to in vitro CD27 costimulation with varlilumabThe CD4⁺ T-cell help signal is transmitted from APC to CD8⁺ T-cells via CD27-CD70 interactionsRole of dendritic cells in the regulation of antitumor immunityCombined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27.A cell-intrinsic requirement for NF-κB-inducing kinase in CD4 and CD8 T cell memory.Tumor necrosis factor receptor/tumor necrosis factor family members in antiviral CD8 T-cell immunity.Role of CD27/CD70 pathway of activation in immunity and tolerance.Searching for "signal 2": costimulation requirements of γδ T cells.OX40:OX40L axis: emerging targets for improving poxvirus-based CD8(+) T-cell vaccines against respiratory virusesThe fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes.The nature of activatory and tolerogenic dendritic cell-derived signal II.The contextual role of TNFR family members in CD8(+) T-cell control of viral infections.Targeting tumor-necrosis factor receptor pathways for tumor immunotherapyATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis.Therapeutic targeting of CD70 and CD27.CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection.Epitope-specific regulation of memory programming by differential duration of antigen presentation to influenza-specific CD8(+) T cells.
P2860
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P2860
CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@ast
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@en
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@nl
type
label
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@ast
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@en
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@nl
prefLabel
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@ast
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@en
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@nl
P2093
P2860
P356
P1476
CD27 sustains survival of CTLs ...... ing autocrine IL-2 production.
@en
P2093
Elise A M Veraar
Jannie Borst
Victor Peperzak
Yanling Xiao
P2860
P304
P356
10.1172/JCI40178
P407
P577
2009-12-01T00:00:00Z