Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice - Wikidata - wikimedia - TriplyDB

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

http://www.wikidata.org/entity/Q34549707

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Hematopoietic stem cells gone rogue.CMML: Clinical and molecular aspects.Epigenetic dysregulation of hematopoietic stem cells and preleukemic state.The role of epigenetics in renal ageing.TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H2S System.The CANTOS Trial: One Important Step for Clinical Cardiology but a Giant Leap for Vascular Biology.Chipping in on clonal hematopoiesis.Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies.Inflammatory Signaling Pathways in Preleukemic and Leukemic Stem Cells.Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia.Elderly Patients Exhibit Stronger Inflammatory Responses during Gout Attacks.Monocyte-Macrophages and T Cells in Atherosclerosis.Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction.Inhibition of microRNA-210 suppresses pro-inflammatory response and reduces acute brain injury of ischemic stroke in mice.Personalized Therapeutics and Pharmacogenomics: Integral to Personalized Health Care.Clonal chromosomal abnormalities appearing in Philadelphia chromosome-negative metaphases during CML treatment.Donor-engrafted CHIP is common among stem cell transplant recipients with unexplained cytopenias.Notable advances 2017.RUNX1 Mutations in Inherited and Sporadic Leukemia.Epigenetics and precision medicine in cardiovascular patients: from basic concepts to the clinical arena.Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.The differential diagnosis of a TP53 genetic testing result.Somatic Mutations and Clonal Hematopoiesis: Unexpected Potential New Drivers of Age-Related Cardiovascular Disease.Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies.TET2: A Novel Epigenetic Regulator and Potential Intervention Target for Atherosclerosis.Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis and Atherogenesis.Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome.Atherosclerosis-prone HSCs.Gout and the risk of myocardial infarction in older adults: a study of Medicare recipients.Underlying Causes and Therapeutic Targeting of the Inflammatory Tumor Microenvironment.CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy High prevalence of focal and multi-focal somatic genetic variants in the human brain Preterm Birth and the Risk of Neurodevelopmental Disorders - Is There a Role for Epigenetic Dysregulation?Be aware, innate immune cells remember

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P2860

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

http://www.wikidata.org/entity/Q34549707

description

2017 nî lūn-bûn

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2017 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2017 թվականի հունվարին հրատարակված գիտական հոդված

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2017年の論文

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2017年論文

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2017年論文

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Clonal hematopoiesis associate ...... osclerosis development in mice

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Clonal hematopoiesis associate ...... osclerosis development in mice

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Clonal hematopoiesis associate ...... osclerosis development in mice

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Clonal hematopoiesis associate ...... osclerosis development in mice

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Clonal hematopoiesis associate ...... osclerosis development in mice

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Clonal hematopoiesis associate ...... osclerosis development in mice

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Cristina Rius

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Karen K Hirschi

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Kathleen A Martin

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Maya N Polackal

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Raja Chakraborty

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Varsha Muralidhar

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P2860

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data.

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis

Age-related clonal hematopoiesis associated with adverse outcomes

Age-related mutations associated with clonal hematopoietic expansion and malignancies

Somatic mutation, genomic variation, and neurological disease

TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

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842-847

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scholarly article

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10.1126/SCIENCE.AAG1381

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6327

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355

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Matthew A. Cooper

Vicente Andrés

Susan MacLauchlan

Avril A.B. Robertson

Sujatha Muralidharan

María A Zuriaga

Jacqueline Vuong

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2017-01-19T00:00:00Z

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28104796

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atherosclerosis

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5542057

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