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Autophagy and its possible roles in nervous system diseases, damage and repair.

Autophagy and its possible roles in nervous system diseases, damage and repair.

http://www.wikidata.org/entity/Q34552018

about

Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy Oxidative stress, mitochondrial dysfunction, and aging Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death Autophagy, nutrition and immunology Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cells Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice Intercellular cross-talk in intracerebral hemorrhage Autophagy fights disease through cellular self-digestion Defective Autophagy, Mitochondrial Clearance and Lipophagy in Niemann-Pick Type B Lymphocytes The metabolism of proline, a stress substrate, modulates carcinogenic pathways Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration Early and sustained activation of autophagy in degenerating axons after spinal cord injury Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons.α-Synuclein mutations cluster around a putative protein loop.Accelerated cell death in Podospora autophagy mutants Mechanisms of acute axonal degeneration in the optic nerve in vivo.Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway.Autophagy induction stabilizes microtubules and promotes axon regeneration after spinal cord injury.Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells.Autophagy is activated and might protect neurons from degeneration after traumatic brain injury.Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models.Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7 Cardiomyocyte death in doxorubicin-induced cardiotoxicity Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.Retrograde axonal transport: pathways to cell death?Autophagy: a double-edged sword for neuronal survival after cerebral ischemia Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells Autophagy in the eye: implications for ocular cell health.Autophagy-regulating small molecules and their therapeutic applications.The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae Autophagy activation aggravates neuronal injury in the hippocampus of vascular dementia rats.Autophagy of mitochondria: a promising therapeutic target for neurodegenerative disease.Lithium reduces apoptosis and autophagy after neonatal hypoxia-ischemia Autophagy, inflammation and neurodegenerative disease.Pharmacological activation of Sirt1 ameliorates polyglutamine-induced toxicity through the regulation of autophagy.Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons Autophagic impairment contributes to systemic inflammation-induced dopaminergic neuron loss in the midbrain.

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P2860

Autophagy and its possible roles in nervous system diseases, damage and repair.

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2005 nî lūn-bûn

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2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2005 թվականի ապրիլին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Autophagy and its possible roles in nervous system diseases, damage and repair.

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Autophagy and its possible roles in nervous system diseases, damage and repair.

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Aviva Tolkovsky

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Brinda Ravikumar

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David C Rubinsztein

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Leonidas Stefanis

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Marian DiFiglia

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Nathaniel Heintz

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Ralph A Nixon

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