Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway - Wikidata - wikimedia - TriplyDB

Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway

Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway

http://www.wikidata.org/entity/Q34573060

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Neuro-invasion by a 'Trojan Horse' strategy and vasculopathy during intrauterine flavivirus infection Emerging roles for the non-canonical IKKs in cancer The selectivity of protein kinase inhibitors: a further update PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics Harnessing systems biology approaches to engineer functional microvascular networks TBK1 protects vacuolar integrity during intracellular bacterial infection.RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia.Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung.The oncometabolite fumarate promotes pseudohypoxia through noncanonical activation of NF-κB signaling Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF.TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation NF-κB and cancer: a paradigm of Yin-Yang.Variations in genes regulating tumor-associated macrophages (TAMs) to predict outcomes of bevacizumab-based treatment in patients with metastatic colorectal cancer: results from TRIBE and FIRE3 trials.Genomics and proteomics approaches in understanding tumor angiogenesis.Advances in targeting IKK and IKK-related kinases for cancer therapy RAMP1 is a direct NKX3.1 target gene up-regulated in prostate cancer that promotes tumorigenesis.TBK1 regulates prostate cancer dormancy through mTOR inhibition.Toll-like receptors, wound healing, and carcinogenesis.Hantavirus GnT elements mediate TRAF3 binding and inhibit RIG-I/TBK1-directed beta interferon transcription by blocking IRF3 phosphorylation.Elevated expression of TANK-binding kinase 1 enhances tamoxifen resistance in breast cancer MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation Endosomal Toll-like receptors in autoimmunity: mechanisms for clinical diversity.IKKε and TBK1 expression in gastric cancer.Inhibitory kappa B Kinases as targets for pharmacological regulation.NF-κB as a target for pancreatic cancer therapy.The biological activity of auranofin: implications for novel treatment of diseases.Negative regulation of TBK1-mediated antiviral immunity.High-throughput transfection and engineering of primary cells and cultured cell lines - an invaluable tool for research as well as drug development.TBK1 Promote Bladder Cancer Cell Proliferation and Migration via Akt Signaling.Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity.Complex Regulation Pattern of IRF3 Activation Revealed by a Novel Dimerization Reporter System.miR-200c enhances radiosensitivity of human breast cancer cells.IκB kinase ε-dependent phosphorylation and degradation of X-linked inhibitor of apoptosis sensitizes cells to virus-induced apoptosis.Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation.Biliary infection may exacerbate biliary cystogenesis through the induction of VEGF in cholangiocytes of the polycystic kidney (PCK) rat Non-canonical IKKs, IKKϵ and TBK1, as novel therapeutic targets in the treatment of non-small cell lung cancer.HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment.A novel function of TBK1 as a target of Cdon in oligodendrocyte differentiation and myelination.Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer.

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Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway

http://www.wikidata.org/entity/Q34573060

description

2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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Identification of proangiogeni ...... ics: TBK1 and the IRF3 pathway

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Identification of proangiogeni ...... ics: TBK1 and the IRF3 pathway

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Identification of proangiogeni ...... ics: TBK1 and the IRF3 pathway

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Identification of proangiogeni ...... ics: TBK1 and the IRF3 pathway

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Proceedings of the National Academy of Sciences of the United States of America

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Identification of proangiogeni ...... ics: TBK1 and the IRF3 pathway

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Christian Korherr

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Hendrik Gille

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Ira Pastan

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Johan Dixelius

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Kerstin Koenig-Hoffmann

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Kristi A Egland

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Rolf Schäfer

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Ulrich Brinkmann

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Initial sequencing and analysis of the human genome

The Sequence of the Human Genome

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

The immunobiology of interferon-gamma inducible protein 10 kD (IP-10): a novel, pleiotropic member of the C-X-C chemokine superfamily

High-throughput functional genomics identifies genes that ameliorate toxicity due to oxidative stress in neuronal HT-22 cells: GFPT2 protects cells against peroxide

Cancer and the chemokine network

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