Unfolded Protein Response (UPR) is activated during normal lens development - Wikidata - wikimedia - TriplyDB

Unfolded Protein Response (UPR) is activated during normal lens development

Unfolded Protein Response (UPR) is activated during normal lens development

http://www.wikidata.org/entity/Q34574453

about

The two Caenorhabditis elegans UDP-glucose:glycoprotein glucosyltransferase homologues have distinct biological functions Oxidative stress, unfolded protein response, and apoptosis in developmental toxicity Juvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane.Selenite cataracts: activation of endoplasmic reticulum stress and loss of Nrf2/Keap1-dependent stress protection The unfolded protein response is activated in connexin 50 mutant mouse lenses.Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4 Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.Modulation of angiogenesis by genetic manipulation of ATF4 in mouse model of oxygen-induced retinopathy [corrected].Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis.Lens ER-stress response during cataract development in Mip-mutant mice.Membrane-tethered transcription factors provide a connection between stress response and developmental pathways.Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses.Age-related cataracts: Role of unfolded protein response, Ca2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection.Signaling and Gene Regulatory Networks in Mammalian Lens Development.A lifetime of stress: ATF6 in development and homeostasis.

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Unfolded Protein Response (UPR) is activated during normal lens development

http://www.wikidata.org/entity/Q34574453

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Unfolded Protein Response (UPR) is activated during normal lens development

@ast

Unfolded Protein Response (UPR) is activated during normal lens development

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Unfolded Protein Response

@nl

type

label

Unfolded Protein Response (UPR) is activated during normal lens development

@ast

Unfolded Protein Response (UPR) is activated during normal lens development

@en

Unfolded Protein Response

@nl

prefLabel

Unfolded Protein Response (UPR) is activated during normal lens development

@ast

Unfolded Protein Response (UPR) is activated during normal lens development

@en

Unfolded Protein Response

@nl

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P356

J.GEP.2010.10.005

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Gene Expression Patterns

P1476

Unfolded Protein Response (UPR) is activated during normal lens development

@en

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Melinda K Duncan

http://www.w3.org/2001/XMLSchema#string

Zeynep Firtina

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

Plasma cell differentiation requires the transcription factor XBP-1

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

Signal integration in the endoplasmic reticulum unfolded protein response

A regulatory link between ER-associated protein degradation and the unfolded-protein response.

Perk is essential for translational regulation and cell survival during the unfolded protein response

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135-143

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scholarly article

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10.1016/J.GEP.2010.10.005

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1-2

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11

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2010-10-31T00:00:00Z

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47660634

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21044701

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3039068

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