Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice.
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Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo.Understanding the Key to Targeting the IGF Axis in Cancer: A Biomarker AssessmentInsulin-like growth factor and epidermal growth factor signaling in breast cancer cell growth: focus on endocrine resistant diseaseTargeting insulin and insulin-like growth factor signaling in breast cancerModulation of insulin-like growth factor-1 receptor and its signaling network for the treatment of cancer: current status and future perspectivesThe Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsAlterations in the insulin-like growth factor system during treatment with diethylstilboestrol in patients with metastatic breast cancerThe IGF system in thyroid cancer: new concepts.Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects.A phase I trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer.Diabetes and cancer: Associations, mechanisms, and implications for medical practice.Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo.Inhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approachIGF-1 regulates Cyr61 induced breast cancer cell proliferation and invasion.ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis.Cell localization, physiology, and nongenomic actions of estrogen receptors.Evaluation of a novel hexavalent humanized anti-IGF-1R antibody and its bivalent parental IgG in diverse cancer cell linesRole of IGF-I in normal mammary development.Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activitySelective estrogen receptor modulators (SERMs) and retinoids in breast cancer chemoprevention.The IGF pathway regulates ERα through a S6K1-dependent mechanism in breast cancer cells.Insulin-like growth factor-dependent proliferation and survival of triple-negative breast cancer cells: implications for therapy.Inhibition of growth, production of insulin-like growth factor-II (IGF-II), and expression of IGF-II mRNA of human cancer cell lines by antagonistic analogs of growth hormone-releasing hormone in vitro.Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor.The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link.Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors.IGFBP-2 and -5: important regulators of normal and neoplastic mammary gland physiologyInsulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factorType 1 Insulin-Like Growth Factor Receptor/Insulin Receptor Substrate 1 Signaling Confers Pathogenic Activity on Breast Tumor Cells Lacking REST.The therapeutic potential of agents targeting the type I insulin-like growth factor receptor.Increased insulin-like growth factor 1 receptor protein expression and gene copy number in small cell lung cancer.Outgrowth of BT-474 human breast cancer cells in immune-deficient mice: a new in vivo model for hormone-dependent breast cancerType I insulin-like growth factor receptor gene expression in normal human breast tissue treated with oestrogen and progesterone.Zinc and cancer: implications for LIV-1 in breast cancer.Expression of insulin-like growth factor I gene in osmoregulatory organs during seawater adaptation of the salmonid fish: possible mode of osmoregulatory action of growth hormoneSuppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells.Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling.Molecular imaging of insulin-like growth factor 1 receptor in cancer.Insulinlike growth factors in human malignancy.Neuropeptide growth factors.
P2860
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P2860
Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice.
description
1989 nî lūn-bûn
@nan
1989 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Blockade of the type I somatom ...... cancer cells in athymic mice.
@ast
Blockade of the type I somatom ...... cancer cells in athymic mice.
@en
Blockade of the type I somatom ...... cancer cells in athymic mice.
@nl
type
label
Blockade of the type I somatom ...... cancer cells in athymic mice.
@ast
Blockade of the type I somatom ...... cancer cells in athymic mice.
@en
Blockade of the type I somatom ...... cancer cells in athymic mice.
@nl
prefLabel
Blockade of the type I somatom ...... cancer cells in athymic mice.
@ast
Blockade of the type I somatom ...... cancer cells in athymic mice.
@en
Blockade of the type I somatom ...... cancer cells in athymic mice.
@nl
P2093
P2860
P356
P1476
Blockade of the type I somatom ...... cancer cells in athymic mice.
@en
P2093
C K Osborne
C L Arteaga
D C Allred
E B Coronado
L J Kitten
P2860
P304
P356
10.1172/JCI114315
P407
P577
1989-11-01T00:00:00Z