A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions.
about
ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptorDynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cellsHER/ErbB receptor interactions and signaling patterns in human mammary epithelial cellsDiversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system.Current status of anti-human epidermal growth factor receptor 2 therapies: predicting and overcoming herceptin resistancePRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling.Targeting the function of the HER2 oncogene in human cancer therapeutics.Molecular imaging of epidermal growth factor receptor kinase activity.Molecular Mechanisms of Trastuzumab Resistance in HER2 Overexpressing Breast CancerActivation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells.Trastuzumab: updated mechanisms of action and resistance in breast cancerThe Therapeutic Challenge of Targeting HER2 in Endometrial CancerNoninvasive imaging and quantification of epidermal growth factor receptor kinase activation in vivo.Resistance to Trastuzumab in Breast Cancer.Tunicamycin enhances the antitumor activity of trastuzumab on breast cancer in vitro and in vivo.A monoclonal antibody targeting ErbB2 domain III inhibits ErbB2 signaling and suppresses the growth of ErbB2-overexpressing breast tumors.The voltage gated Ca(2+)-channel Cav3.2 and therapeutic responses in breast cancerMulticenter phase II study of neoadjuvant lapatinib and trastuzumab with hormonal therapy and without chemotherapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer: TBCRC 006Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor.The ERBB3 receptor in cancer and cancer gene therapyLigand-induced ErbB receptor dimerization.Dynamic analysis of the epidermal growth factor (EGF) receptor-ErbB2-ErbB3 protein network by luciferase fragment complementation imagingClinical activities of the epidermal growth factor receptor family inhibitors in breast cancer.Interaction of antibodies with ErbB receptor extracellular regions.Biased agonism as a mechanism for differential signaling by chemokine receptors.Mammalian two-hybrids come of age.HER2 monoclonal antibodies that do not interfere with receptor heterodimerization-mediated signaling induce effective internalization and represent valuable components for rational antibody-drug conjugate designTransmembrane helix-helix interactions involved in ErbB receptor signaling.Development of trastuzumab-resistant human gastric carcinoma cell lines and mechanisms of drug resistance.Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors.Structural basis of a novel heterodimeric Fc for bispecific antibody production.A high-performance, non-radioactive potency assay for measuring cytotoxicity: A full substitute of the chromium-release assay targeting the regulatory-compliance objective.Prognostic value of phosphorylated HER2 in HER2-positive breast cancer patients treated with adjuvant trastuzumab.Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers
P2860
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P2860
A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions.
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A system for quantifying dynam ...... modulating ErbB2 interactions.
@ast
A system for quantifying dynam ...... modulating ErbB2 interactions.
@en
A system for quantifying dynam ...... modulating ErbB2 interactions.
@nl
type
label
A system for quantifying dynam ...... modulating ErbB2 interactions.
@ast
A system for quantifying dynam ...... modulating ErbB2 interactions.
@en
A system for quantifying dynam ...... modulating ErbB2 interactions.
@nl
prefLabel
A system for quantifying dynam ...... modulating ErbB2 interactions.
@ast
A system for quantifying dynam ...... modulating ErbB2 interactions.
@en
A system for quantifying dynam ...... modulating ErbB2 interactions.
@nl
P2093
P2860
P921
P356
P1476
A system for quantifying dynam ...... modulating ErbB2 interactions.
@en
P2093
C L Casipit
J H Pomerantz
R Doyonnas
T S Wehrman
P2860
P304
19063-19068
P356
10.1073/PNAS.0605218103
P407
P577
2006-12-05T00:00:00Z