Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains - Wikidata - wikimedia - TriplyDB

Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains

Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains

http://www.wikidata.org/entity/Q34596733

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Total synthesis of bryostatin 7 via C-C bond-forming hydrogenation Postischemic PKC activation rescues retrograde and anterograde long-term memory Bryostatin improves survival and reduces ischemic brain injury in aged rats after acute ischemic stroke Bryostatin-1 Restores Blood Brain Barrier Integrity following Blast-Induced Traumatic Brain Injury DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke Bryostatin Effects on Cognitive Function and PKCɛ in Alzheimer's Disease Phase IIa and Expanded Access Trials.Total synthesis of bryostatin 16 using a Pd-catalyzed diyne coupling as macrocyclization method and synthesis of C20-epi-bryostatin 7 as a potent anticancer agent.Bryostatins: biological context and biotechnological prospects.Total synthesis of bryostatin 9 Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis Chronic cerebral ischaemia forms new cholinergic mechanisms of learning and memory.Total synthesis of bryostatin 1 The bryostatin 1 A-ring acetate is not the critical determinant for antagonism of phorbol ester-induced biological responses.Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection.Improved protein kinase C affinity through final step diversification of a simplified salicylate-derived bryostatin analog scaffold.Lead Diversification through a Prins-Driven Macrocyclization Strategy: Application to C13-Diversified Bryostatin Analogues.Toward a biorelevant structure of protein kinase C bound modulators: design, synthesis, and evaluation of labeled bryostatin analogues for analysis with rotational echo double resonance NMR spectroscopy Selective estrogen receptor modulators (SERMs) enhance neurogenesis and spine density following focal cerebral ischemia Common mechanisms of Alzheimer's disease and ischemic stroke: the role of protein kinase C in the progression of age-related neurodegeneration."Picolog," a synthetically-available bryostatin analog, inhibits growth of MYC-induced lymphoma in vivo.Total synthesis of bryostatins: the development of methodology for the atom-economic and stereoselective synthesis of the ring C subunit.DOR activation inhibits anoxic/ischemic Na+ influx through Na+ channels via PKC mechanisms in the cortex Post ischemia intermittent hypoxia induces hippocampal neurogenesis and synaptic alterations and alleviates long-term memory impairment.Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death.Microbial natural products: molecular blueprints for antitumor drugs.Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products.Bryostatin and its synthetic analog, picolog rescue dermal fibroblasts from prolonged stress and contribute to survival and rejuvenation of human skin equivalents.Protein kinase C epsilon delays latency until anoxic depolarization through arc expression and GluR2 internalization.Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity.Reduction of beta-amyloid levels by novel protein kinase C(epsilon) activators.Acyl Ghrelin Improves Synapse Recovery in an In Vitro Model of Postanoxic Encephalopathy.Phorbol 12-Myristate 13-Acetate Enhances Long-Term Potentiation in the Hippocampus through Activation of Protein Kinase Cδ and ε.Protein kinase C-regulated aβ production and clearance.Protein Kinase Cϵ (PKCϵ) Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95 PKC Activation Counteracts ADAM10 Deficit in HuD-Silenced Neuroblastoma Cells.Concise synthesis of the bryostatin A-ring via consecutive C-C bond forming transfer hydrogenations.Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters.Potential Therapeutics for Vascular Cognitive Impairment and Dementia.2.45 GHz Microwave radiation impairs hippocampal learning and spatial memory: Involvement of local stress mechanism induced suppression of iGluR/ERK/CREB signaling.

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Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains

http://www.wikidata.org/entity/Q34596733

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Poststroke neuronal rescue and ...... otein kinase C in adult brains

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Poststroke neuronal rescue and ...... otein kinase C in adult brains

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Poststroke neuronal rescue and ...... otein kinase C in adult brains

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Poststroke neuronal rescue and ...... otein kinase C in adult brains

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Poststroke neuronal rescue and ...... otein kinase C in adult brains

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Poststroke neuronal rescue and ...... otein kinase C in adult brains

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PNAS.0805952105

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Proceedings of the National Academy of Sciences of the United States of America

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Poststroke neuronal rescue and ...... otein kinase C in adult brains

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P2093

Daniel L Alkon

http://www.w3.org/2001/XMLSchema#string

Jarin Hongpaisan

http://www.w3.org/2001/XMLSchema#string

Miao-Kun Sun

http://www.w3.org/2001/XMLSchema#string

Thomas J Nelson

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P2860

Ischemic cell death in brain neurons

Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors

ADAM-10 over-expression increases cortical synaptogenesis

A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC

Imaging-guided acute ischemic stroke therapy: From "time is brain" to "physiology is brain".

DeltaPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo.

The role of cerebral ischemia in Alzheimer's disease.

Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning

Cerebral microvascular pathology in aging and Alzheimer's disease.

Delayed neuronal death in the gerbil hippocampus following ischemia.

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13620-13625

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10.1073/PNAS.0805952105

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36

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105

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2008-09-03T00:00:00Z

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23235549

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18768786

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2533239

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