Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. - Wikidata - wikimedia - TriplyDB

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

http://www.wikidata.org/entity/Q34621634

about

Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1 The role of oxidative stress in Parkinson's disease Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1 Human DJ-1 and its homologs are novel glyoxalases Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling microRNAs: Emerging Targets Regulating Oxidative Stress in the Models of Parkinson's Disease Potential Role of Epigenetic Mechanism in Manganese Induced Neurotoxicity Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson's Disease Parkinson's disease proteins: Novel mitochondrial targets for cardioprotection Mitochondria: A Therapeutic Target for Parkinson's Disease?Deconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purpose Oxidative stress and Parkinson's disease Mitochondrial biology and Parkinson's disease Mouse models of Parkinson's disease associated with mitochondrial dysfunction Genetically engineered mouse models of Parkinson's disease Parkinson's disease, insulin resistance and novel agents of neuroprotection Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder Mitochondrial dysfunction and oxidative stress in Parkinson's disease Network analysis reveals common host protein/s modulating pathogenesis of neurotropic viruses Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase Parkinson's disease as a result of aging Autophagosome dynamics in neurodegeneration at a glance Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes Evidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1 Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease Mitophagy mechanisms and role in human diseases DJ-1 knock-down impairs astrocyte mitochondrial function.Mitochondrial disorders and the eye.Mechanisms of Parkinson's disease-related proteins in mediating secondary brain damage after cerebral ischemia.The Role of Interleukin-18, Oxidative Stress and Metabolic Syndrome in Alzheimer's Disease.Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption.A plant DJ-1 homolog is essential for Arabidopsis thaliana chloroplast development.Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1 DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress.

P2860

Q24297033-76B75A53-B03B-4248-A9AF-BA80EDEBB0E4 Q24301357-B6001A41-D696-4138-865D-5B7D2976CE0B Q24307946-8B037C3C-6667-4E1D-A0F0-FC7271600A8A Q24315046-B80B975B-56B1-45A1-AD1E-B9B045EA55E6 Q24316421-1DE0282C-285D-4812-A48B-5382F2A58B2A Q24322579-E9981551-446E-4FFE-BE45-D1BB10F119C4 Q24339442-339BC21D-5138-4FED-9881-3D10ED5057AD Q24608960-266482F6-7E0B-4ECE-93EF-C31EBBDB670A Q26738440-52F25E44-ED9A-42C1-A4C6-51A2062A3E24 Q26744563-0EF96139-003B-4F55-9D24-4DF9DEB5E5AB Q26746897-F55FDEEF-F3A7-4380-8A09-F1E179A6FEC5 Q26781796-09699FB4-DD39-4CE2-9608-50A75388C91E Q26784216-1B61ADDC-1657-4C0C-85C3-07760A0DA322 Q26785491-31607C2F-2078-4C60-B11B-7D3FE1E1D684 Q26798897-0FAB9F94-DA7D-4B15-A5B2-0C707F00B41B Q26824090-9A8620F5-0552-4533-A2A8-22894623824F Q26829851-9B11D5AB-F804-4363-97DF-BDDD3B5494B9 Q26852964-91FDE570-9BAA-4FFB-AE17-FB0FCF693A41 Q26853311-4F867922-0DF1-4798-96CF-8F64D4B9A5F2 Q27001551-F65277E2-2D39-449E-8F13-DBE701F6B068 Q27014051-4564FCD5-E68B-4473-BBFE-6F121CE742C3 Q27468796-7DA7964C-0989-4353-AB0B-D9FFD5E09C9C Q27683814-A221EFD5-A0AC-4261-B240-E80D1E6C2B65 Q27937729-986FA9A9-D57C-4727-A988-A43773860E6E Q28084395-46C5E996-206F-451A-A54E-7C913295A1B2 Q28084804-07C22156-F182-45F2-9AEE-7195031C8452 Q28115112-900A3C15-9609-4CB1-B0C5-C4B1E392CE0C Q28258696-4074B655-035E-4C62-8C57-0EF3FBBCC88F Q28280353-1886BA96-4DE7-4028-9A48-85B2D4CE7705 Q28390998-EA0E3C71-92CC-4B0B-B5D4-9A1B1CEE791C Q30527966-5847D334-8BA7-4492-A902-ADB568A76197 Q33702120-6D030E32-2911-4157-87C5-25BA5FFF9328 Q33727623-4AE40976-EDF5-4925-B89E-59E4DBDE8E6A Q33737263-EB3B9A59-4DAF-4393-9182-358A193AAE79 Q33737338-F83D24F1-9638-496D-9337-45D15241E9E1 Q34008915-17B9C0FB-72E0-477D-B404-EE7325009678 Q34014666-A2F4EF28-3494-423E-A82C-D95845770330 Q34048830-9B8B79CE-7640-482B-B9E8-2ADF4883A15E Q34079628-D67E0E6D-2810-4909-857C-C647F1F70FDD Q34166108-A81417D5-CE63-4292-BF1D-49BFF8C291F9

P2860

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

http://www.wikidata.org/entity/Q34621634

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@ast

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@en

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@nl

type

label

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@ast

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@en

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@nl

prefLabel

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@ast

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@en

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@nl

P1433

Q34621634-4112292E-95D0-4DEA-BDC1-25F447EE9C16

P1476

Q34621634-912DD164-B6B6-483B-9BE5-E7BF3372C5FD

P2093

Q34621634-0CA14D0F-52B9-4F5A-ABB6-F3203D100DFA

Q34621634-0F9063F1-6DA7-4FCB-9CE8-46CE4B9BAF20

Q34621634-4F18BF53-0715-4FA3-9F93-4829D6F3E347

Q34621634-5132F1C6-8B0E-4CB6-AA90-BE1CB9017278

Q34621634-7140C0FD-ADDF-491C-85BF-3E91CC04C8A9

Q34621634-7F3CE038-2FD1-41DE-AEC6-8EFE5584983E

Q34621634-854C7ED4-C8A7-4B74-A231-CCFF1BED9E4E

Q34621634-90823E63-A389-41E8-A769-028A424F3DD6

Q34621634-9CC4AB0F-DF31-4889-8F03-FBE2B4579DFA

Q34621634-B97078E9-C899-445C-98FC-081E1B95D688

P304

Q34621634-EB7CC968-15FC-4E53-929E-5201825E8214

P31

Q34621634-D757F334-6943-44BA-ADAC-DF506F89A272

P356

Q34621634-FCA7E902-FCFB-4FEA-A27E-507A520F159F

P433

Q34621634-0CEC28FF-3A6B-4AF9-BB01-DDABFCC95F8F

P478

Q34621634-CE465746-51CE-4BBC-A50F-E95343EE51D9

P50

Q34621634-01355622-A139-4143-973C-DB263A6120BD

Q34621634-408FBB90-46C3-4831-920E-10EF5CE97A86

Q34621634-4930A334-89F9-4A58-9193-1CA0EC306179

Q34621634-600C18C1-11F4-4704-B9F5-69DDFF7427AE

Q34621634-9BE4F976-A09D-4531-888C-A007AFD805F6

Q34621634-C79886A0-866E-4BDE-9EF2-22C8FA6D29C7

P577

Q34621634-F29022C2-E8EE-4AC5-832F-0CF602E0F041

P5875

Q34621634-4D83190E-04A6-42EF-8E22-D69D8B793E45

P698

Q34621634-B4E9F904-7559-4EC3-A18F-8DA54A0D8694

P921

Q34621634-4C26C156-16F2-4337-A834-9274D4601817

P356

P1433

Human Molecular Genetics

P1476

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

@en

P2093

A Jahani-Asl

http://www.w3.org/2001/XMLSchema#string

A K Lutz

http://www.w3.org/2001/XMLSchema#string

C X Chen

http://www.w3.org/2001/XMLSchema#string

E A Fon

http://www.w3.org/2001/XMLSchema#string

E L Seifert

http://www.w3.org/2001/XMLSchema#string

I Irrcher

http://www.w3.org/2001/XMLSchema#string

J G MacLaurin

http://www.w3.org/2001/XMLSchema#string

L Bevilacqua

http://www.w3.org/2001/XMLSchema#string

M Phillips

http://www.w3.org/2001/XMLSchema#string

P Rippstein

http://www.w3.org/2001/XMLSchema#string

P304

3734-3746

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/HMG/DDQ288

http://www.w3.org/2001/XMLSchema#string

P433

19

http://www.w3.org/2001/XMLSchema#string

P478

19

http://www.w3.org/2001/XMLSchema#string

P50

Mary-Ellen Harper

Konstanze F Winklhofer

Heidi M McBride

Hossein Aleyasin

Maxime Rousseaux

P577

2010-07-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

45271766

http://www.w3.org/2001/XMLSchema#string

P698

20639397

http://www.w3.org/2001/XMLSchema#string

P921

Parkinson's disease