A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases.
about
Mitochondrial translation and beyond: processes implicated in combined oxidative phosphorylation deficienciesTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesMitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's DiseasesReperfusion promotes mitochondrial biogenesis following focal cerebral ischemia in ratsThe yeast complex I equivalent NADH dehydrogenase rescues pink1 mutantsKey Targets for Multi-Target Ligands Designed to Combat NeurodegenerationCholine dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagyHuman PON1, a biomarker of risk of disease and exposureParkin is protective against proteotoxic stress in a transgenic zebrafish modelReduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1Sex differences in mitochondrial biogenesis determine neuronal death and survival in response to oxygen glucose deprivation and reoxygenation.Nitrated alpha-synuclein and microglial neuroregulatory activities.Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factorsBridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity.Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease modelsRegional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport.Mitochondrial morphogenesis, distribution, and Parkinson disease: insights from PINK1Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.Therapeutic potential of fluoxetine in neurological disorders.Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin.Acute morphine treatments alleviate tremor in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys.Paeonolum protects against MPP(+)-induced neurotoxicity in zebrafish and PC12 cells.Neurodegenerative Diseases: Multifactorial Conformational Diseases and Their Therapeutic InterventionsDissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis.Rotenone Susceptibility Phenotype in Olfactory Derived Patient Cells as a Model of Idiopathic Parkinson's DiseaseParkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration.Infantile Progressive Hepatoencephalomyopathy with Combined OXPHOS Deficiency due to Mutations in the Mitochondrial Translation Elongation Factor Gene GFM1.Quality control of mitochondria: protection against neurodegeneration and ageing.Mitochondrial hsp60 chaperonopathy causes an autosomal-recessive neurodegenerative disorder linked to brain hypomyelination and leukodystrophy.Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease.Cognitive Impairment Associated with Parkinson's Disease: Role of Mitochondria.Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial traffickingAdvances with microRNAs in Parkinson's disease research.Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury.Searching for MIND: microRNAs in neurodegenerative diseases.Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer.Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic modelsCell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps.Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death.
P2860
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P2860
A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A cell biological perspective ...... er neurodegenerative diseases.
@ast
A cell biological perspective ...... er neurodegenerative diseases.
@en
A cell biological perspective ...... er neurodegenerative diseases.
@nl
type
label
A cell biological perspective ...... er neurodegenerative diseases.
@ast
A cell biological perspective ...... er neurodegenerative diseases.
@en
A cell biological perspective ...... er neurodegenerative diseases.
@nl
prefLabel
A cell biological perspective ...... er neurodegenerative diseases.
@ast
A cell biological perspective ...... er neurodegenerative diseases.
@en
A cell biological perspective ...... er neurodegenerative diseases.
@nl
P356
P1476
A cell biological perspective ...... er neurodegenerative diseases.
@en
P2093
Vanessa A Morais
Wim Mandemakers
P304
P356
10.1242/JCS.03443
P407
P577
2007-05-01T00:00:00Z