Fibrillins 1 and 2 perform partially overlapping functions during aortic development. - Wikidata - wikimedia - TriplyDB

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

http://www.wikidata.org/entity/Q34644635

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The evolution of extracellular fibrillins and their functional domains Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation Latent TGF-beta-binding protein 2 binds to DANCE/fibulin-5 and regulates elastic fiber assembly Essential role for fibrillin-2 in zebrafish notochord and vascular morphogenesis Fibulin-4 regulates expression of the tropoelastin gene and consequent elastic-fibre formation by human fibroblasts Perforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysm Functional consequences of homocysteinylation of the elastic fiber proteins fibrillin-1 and tropoelastin The molecular genetics of Marfan syndrome and related disorders Genetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and function Morphological Characterisation of Unstained and Intact Tissue Micro-architecture by X-ray Computed Micro- and Nano-Tomography Microenvironmental regulation by fibrillin-1 Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia Generation of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblasts Genes responsive to low-intensity pulsed ultrasound in MC3T3-E1 preosteoblast cells.In vivo studies of mutant fibrillin-1 microfibrils Discrete contributions of elastic fiber components to arterial development and mechanical compliance.Fibulin-2 and fibulin-5 cooperatively function to form the internal elastic lamina and protect from vascular injury.Defining elastic fiber interactions by molecular fishing: an affinity purification and mass spectrometry approach.Biogenesis and function of fibrillin assemblies.The extracellular matrix protein MAGP1 supports thermogenesis and protects against obesity and diabetes through regulation of TGF-β Extracellular matrix molecules facilitating vascular biointegration Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression An ADAMTSL2 founder mutation causes Musladin-Lueke Syndrome, a heritable disorder of beagle dogs, featuring stiff skin and joint contractures.Unraveling the mechanism of elastic fiber assembly: The roles of short fibulins Microfibril structure masks fibrillin-2 in postnatal tissues Versican facilitates chondrocyte differentiation and regulates joint morphogenesis Fibrillin-2 is dispensable for peripheral nerve development, myelination and regeneration.Microfibril-associated glycoprotein-1, an extracellular matrix regulator of bone remodeling.Drug-based therapies for vascular disease in Marfan syndrome: from mouse models to human patients.Fibulin-4 and fibulin-5 in elastogenesis and beyond: Insights from mouse and human studies.TGFBR1 mutations associated with Loeys-Dietz syndrome are inactivating.Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production Co-expression of FBN1 with mesenchyme-specific genes in mouse cell lines: implications for phenotypic variability in Marfan syndrome Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome Elastogenesis at the onset of human cardiac valve development.Fibrillin assemblies: extracellular determinants of tissue formation and fibrosis Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo Fibrillin-1 genetic deficiency leads to pathological ageing of arteries in mice.

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P2860

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

http://www.wikidata.org/entity/Q34644635

description

2005 nî lūn-bûn

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2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@ast

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@en

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@nl

type

label

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@ast

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@en

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@nl

prefLabel

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@ast

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@en

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@nl

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Journal of Biological Chemistry

P1476

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

@en

P2093

Alexander Kerkis

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Barry Starcher

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Brett Lenart

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Christian A Merkel

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Douglas R Keene

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Emilio Arteaga-Solis

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Francesco Ramirez

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Luca Carta

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Lygia Pereira

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Lynn Y Sakai

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P2860

Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome

Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo

CYR61 (CCN1) is essential for placental development and vascular integrity

Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1

Regulation of limb patterning by extracellular microfibrils

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Fibulin-5/DANCE is essential for elastogenesis in vivo

Elastic fiber homeostasis requires lysyl oxidase-like 1 protein

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.

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8016-8023

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10.1074/JBC.M511599200

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12

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281

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2005-12-28T00:00:00Z

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16407178

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3052983

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