Cdc20: a WD40 activator for a cell cycle degradation machine.
about
The HTLV-1 Tax interactomeDishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1.APC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathwayp31comet blocks Mad2 activation through structural mimicryPharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damageStxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradationBubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis.Identification of a physiological E2 module for the human anaphase-promoting complexControl of cell growth by the SCF and APC/C ubiquitin ligasesContribution of the Type II Chaperonin, TRiC/CCT, to OncogenesisFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisTargeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit.MASTL(Greatwall) regulates DNA damage responses by coordinating mitotic entry after checkpoint recovery and APC/C activationThe zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylationInsights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 DimerStructure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1Structural analysis of human Cdc20 supports multisite degron recognition by APC/CStructure of human Mad1 C-terminal domain reveals its involvement in kinetochore targetingPseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation.Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.Mechanisms of pseudosubstrate inhibition of the anaphase promoting complex by Acm1.Ama1p-activated anaphase-promoting complex regulates the destruction of Cdc20p during meiosis II.Modulation of the mitotic regulatory network by APC-dependent destruction of the Cdh1 inhibitor Acm1.A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete developmentTranscriptional control of mitosis: deregulation and cancerThe deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosisIn-silico modeling of the mitotic spindle assembly checkpointMassively parallel sequencing and analysis of the Necator americanus transcriptomeQuantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exitThe HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transitionSystematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches.Inhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit.BubR1 is modified by sumoylation during mitotic progressionSumoylated BubR1 plays an important role in chromosome segregation and mitotic timing.Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.Deregulation of Rb-E2F1 axis causes chromosomal instability by engaging the transactivation function of Cdc20-anaphase-promoting complex/cyclosome.Conserved CDC20 cell cycle functions are carried out by two of the five isoforms in Arabidopsis thalianaMUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patientsOverexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation.
P2860
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P2860
Cdc20: a WD40 activator for a cell cycle degradation machine.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Cdc20: a WD40 activator for a cell cycle degradation machine.
@ast
Cdc20: a WD40 activator for a cell cycle degradation machine.
@en
Cdc20: a WD40 activator for a cell cycle degradation machine.
@nl
type
label
Cdc20: a WD40 activator for a cell cycle degradation machine.
@ast
Cdc20: a WD40 activator for a cell cycle degradation machine.
@en
Cdc20: a WD40 activator for a cell cycle degradation machine.
@nl
prefLabel
Cdc20: a WD40 activator for a cell cycle degradation machine.
@ast
Cdc20: a WD40 activator for a cell cycle degradation machine.
@en
Cdc20: a WD40 activator for a cell cycle degradation machine.
@nl
P1433
P1476
Cdc20: a WD40 activator for a cell cycle degradation machine.
@en
P2093
Hongtao Yu
P356
10.1016/J.MOLCEL.2007.06.009
P577
2007-07-01T00:00:00Z