Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase.
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PLEKHG2 promotes heterotrimeric G protein βγ-stimulated lymphocyte migration via Rac and Cdc42 activation and actin polymerization.Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironmentsRegulation and function of P-Rex family Rac-GEFsCool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretionRegulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.Activation of the A(3) adenosine receptor inhibits fMLP-induced Rac activation in mouse bone marrow neutrophils.Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.Shuttling and translocation of heterotrimeric G proteins and Ras.Frontier of epilepsy research - mTOR signaling pathway.Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells.Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1.Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets.Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells.Rac signaling in breast cancer: a tale of GEFs and GAPs.The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.Rac1 Activation Caused by Membrane Translocation of a Guanine Nucleotide Exchange Factor in Akt2-Mediated Insulin Signaling in Mouse Skeletal MuscleSynergistic induction of cancer cell migration regulated by Gβγ and phosphatidylinositol 3-kinase.p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALINGStructural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.G protein-coupled receptor-promoted trafficking of Gbeta1gamma2 leads to AKT activation at endosomes via a mechanism mediated by Gbeta1gamma2-Rab11a interactionGEFs in growth factor signaling.The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexesUpregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.Chorionic gonadotropin regulates prostaglandin E synthase via a phosphatidylinositol 3-kinase-extracellular regulatory kinase pathway in a human endometrial epithelial cell line: implications for endometrial responses for embryo implantation.Characterization of a P-Rex1 gene signature in breast cancer cellsCrossroads of PI3K and Rac pathways.MADD is a downstream target of PTEN in triggering apoptosis.Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP.Multisite phosphorylation of P-Rex1 by protein kinase C.The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α.A Rac1-independent role for P-Rex1 in melanoblasts.P-Rex2, a Rac-guanine nucleotide exchange factor, is expressed selectively in ribbon synaptic terminals of the mouse retina.Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.
P2860
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P2860
Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@ast
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@en
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@nl
type
label
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@ast
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@en
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@nl
prefLabel
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@ast
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@en
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@nl
P2093
P2860
P356
P1476
Membrane translocation of P-Re ...... and phosphoinositide 3-kinase.
@en
P2093
Karen E Anderson
Marcus Thelen
Mark A Barber
Sarah Donald
Sylvia Thelen
P2860
P304
29967-29976
P356
10.1074/JBC.M701877200
P407
P50
P577
2007-08-13T00:00:00Z