about
Quantitative in vivo solubility and reconstitution of truncated circular permutants of green fluorescent proteinProtein aggregation and its impact on product qualityMapping the conformational dynamics and pathways of spontaneous steric zipper Peptide oligomerizationCharacterization of oligomers of heterogeneous size as precursors of amyloid fibril nucleation of an SH3 domain: an experimental kinetics study.Modulating non-native aggregation and electrostatic protein-protein interactions with computationally designed single-point mutationsUnderstanding the relationship between biotherapeutic protein stability and solid-liquid interfacial shear in constant region mutants of IgG1 and IgG4Aggregation Kinetics for IgG1-Based Monoclonal Antibody Therapeutics.Controlling adsorption and passivation properties of bovine serum albumin on silica surfaces by ionic strength modulation and cross-linking.Reduction of the C191-C220 disulfide of α-chymotrypsinogen A reduces nucleation barriers for aggregation.Aggregation mechanism of an IgG2 and two IgG1 monoclonal antibodies at low pH: from oligomers to larger aggregates.Conformational stability as a design target to control protein aggregation.Model discrimination and mechanistic interpretation of kinetic data in protein aggregation studies.Glycosylation of therapeutic proteins: an effective strategy to optimize efficacyProtein-protein interactions in dilute to concentrated solutions: α-chymotrypsinogen in acidic conditions.Aggregation of a multidomain protein: a coagulation mechanism governs aggregation of a model IgG1 antibody under weak thermal stressTherapeutic protein aggregation: mechanisms, design, and control.Non-native aggregation of recombinant human granulocyte-colony stimulating factor under simulated process stress conditions.In vitro aggregation behavior of a non-amyloidogenic λ light chain dimer deriving from U266 multiple myeloma cells.A mechanistic model for amorphous protein aggregation of immunoglobulin-like domains.A model of threshold behavior reveals rescue mechanisms of bystander proteins in conformational diseasesWeak protein interactions and pH- and temperature-dependent aggregation of human Fc1.Identifying protein aggregation mechanisms and quantifying aggregation rates from combined monomer depletion and continuous scatteringModulation of self-association and subsequent fibril formation in an alanine-rich helical polypeptide.Effects of glycosylation on the stability of protein pharmaceuticals.Native-like aggregates of factor VIII are immunogenic in von Willebrand factor deficient and hemophilia a miceLumry-Eyring nucleated-polymerization model of protein aggregation kinetics. 2. Competing growth via condensation and chain polymerization.The αA66-80 peptide interacts with soluble α-crystallin and induces its aggregation and precipitation: a contribution to age-related cataract formation.Phosphorylation dependence of hsp27 multimeric size and molecular chaperone functionEnhanced extraction of bovine serum albumin with aqueous biphasic systems of phosphonium- and ammonium-based ionic liquids.Structure and thermodynamics of colloidal protein cluster formation: comparison of square-well and simple dipolar models.Mechanism of suppression of protein aggregation by α-crystallin.Aggregation of a monoclonal antibody induced by adsorption to stainless steelAmyloid structure--one but not the same: the many levels of fibrillar polymorphism.Aggregates in monoclonal antibody manufacturing processes.Protein particulate detection issues in biotherapeutics development--current status.Non-Arrhenius protein aggregation.A multiscale view of therapeutic protein aggregation: a colloid science perspective.A minimal conformational switching-dependent model for amyloid self-assembly.Analysis of IgG kinetic stability by differential scanning calorimetry, probe fluorescence and light scattering.Quantitative characterization by asymmetrical flow field-flow fractionation of IgG thermal aggregation with and without polymer protective agents.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Non-native protein aggregation kinetics.
@ast
Non-native protein aggregation kinetics.
@en
Non-native protein aggregation kinetics.
@nl
type
label
Non-native protein aggregation kinetics.
@ast
Non-native protein aggregation kinetics.
@en
Non-native protein aggregation kinetics.
@nl
prefLabel
Non-native protein aggregation kinetics.
@ast
Non-native protein aggregation kinetics.
@en
Non-native protein aggregation kinetics.
@nl
P356
P1476
Non-native protein aggregation kinetics.
@en
P2093
Christopher J Roberts
P304
P356
10.1002/BIT.21627
P577
2007-12-01T00:00:00Z