Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice. - Wikidata - wikimedia - TriplyDB

Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice.

Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice.

http://www.wikidata.org/entity/Q34675871

about

Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection Animal models of hemophilia Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.Comparison of factor VIII transgenes bioengineered for improved expression in gene therapy of hemophilia A Adeno-associated virus vectors and hematology Gene therapy for the hemophilias.Gene therapy for hemophilia.Advancements in gene transfer-based therapy for hemophilia A.Biosafety assessment of site-directed transgene integration in human umbilical cord-lining cells.Haemophilias: advances towards genetic engineering replacement therapy.Gene therapy for haemophilia.Microspheres for controlled release drug delivery.Long-term expression of human coagulation factor VIII and correction of hemophilia A after in vivo retroviral gene transfer in factor VIII-deficient mice.Gene transfer to epidermal stem cells: implications for tissue engineering.Adenoviral vectors: development and application.Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein.Endothelial progenitor cell-based therapy for hemophilia A.PLA micro- and nano-particles.Analysis of factor VIII mediated suppression of lentiviral vector titres.Recombinant factor VIII expression in hematopoietic cells following lentiviral transduction.Prospects for the use of artificial chromosomes and minichromosome-like episomes in gene therapy.Expression of human coagulation factor VIII in adipocytes transduced with the simian immunodeficiency virus agmTYO1-based vector for hemophilia A gene therapy.Microbubble ultrasound improves the efficiency of gene transduction in skeletal muscle in vivo with reduced tissue damage.Efficient adenoviral vector transduction and expression of functional human factor VIII in cultured primary human hepatocytes.

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P2860

Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice.

http://www.wikidata.org/entity/Q34675871

description

1995 nî lūn-bûn

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1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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1995 թվականի փետրվարին հրատարակված գիտական հոդված

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Proceedings of the National Academy of Sciences of the United States of America

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Gene therapy for hemophilia A: ...... n factor VIII in vivo in mice.

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Belloni P

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Berns A

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Cohen LK

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P2860

The scanning model for translation: an update

Use of recombinant antihemophilic factor in the treatment of two patients with classic hemophilia

Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity

Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII)

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

Characterization of the polypeptide composition of human factor VIII:C and the nucleotide sequence and expression of the human kidney cDNA.

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts.

Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopes

In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery.

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1023-1027

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15335854

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7862626

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Coagulation factor VIII

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42629

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