Increased p53 activity does not accelerate telomere-driven ageing. - Wikidata - wikimedia - TriplyDB

Increased p53 activity does not accelerate telomere-driven ageing.

Increased p53 activity does not accelerate telomere-driven ageing.

http://www.wikidata.org/entity/Q34683069

about

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer Regulation of glucose metabolism by p53: emerging new roles for the tumor suppressor Two faces of p53: aging and tumor suppression Telomeres in aging and disease: lessons from zebrafish Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.Telomere shortening reduces regenerative capacity after acute kidney injury.p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo.Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status.Removing all obstacles: a critical role for p53 in promoting tissue renewal Telomeres in cancer and ageing.Increased Arf/p53 activity in stem cells, aging and cancer.Regulation of senescence in cancer and aging.The longest telomeres: a general signature of adult stem cell compartments.Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis.Targeting the p53 signaling pathway in cancer therapy - the promises, challenges and perils.Cellular senescence and organismal aging.Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres.A metabolic signature predicts biological age in mice.Aging by epigenetics--a consequence of chromatin damage?REGγ deficiency promotes premature aging via the casein kinase 1 pathway.TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis.A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance.The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior.Jun dimerization protein 2 controls senescence and differentiation via regulating histone modification.The p53 tumor suppressor protein regulates hematopoietic stem cell fate.How will telomeric complex be further contributed to our longevity? - the potential novel biomarkers of telomere complex counteracting both aging and cancer.Battling cancer on many fronts. Meeting on New Battlefields in Human Cancer--Attacking in Many Fronts.Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16Ink4a-pRb and Arf-p53 pathways.Tissue damage and senescence provide critical signals for cellular reprogramming in vivo.AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer

P2860

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P2860

Increased p53 activity does not accelerate telomere-driven ageing.

http://www.wikidata.org/entity/Q34683069

description

2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Increased p53 activity does not accelerate telomere-driven ageing.

@ast

Increased p53 activity does not accelerate telomere-driven ageing.

@en

Increased p53 activity does not accelerate telomere-driven ageing.

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type

label

Increased p53 activity does not accelerate telomere-driven ageing.

@ast

Increased p53 activity does not accelerate telomere-driven ageing.

@en

Increased p53 activity does not accelerate telomere-driven ageing.

@nl

prefLabel

Increased p53 activity does not accelerate telomere-driven ageing.

@ast

Increased p53 activity does not accelerate telomere-driven ageing.

@en

Increased p53 activity does not accelerate telomere-driven ageing.

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Increased p53 activity does not accelerate telomere-driven ageing.

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Antonia Tomás-Loba

http://www.w3.org/2001/XMLSchema#string

Isabel García-Cao

http://www.w3.org/2001/XMLSchema#string

Juan Martín-Caballero

http://www.w3.org/2001/XMLSchema#string

Juana M Flores

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Marta García-Cao

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Peter Klatt

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P2860

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

Aging and genome maintenance: lessons from the mouse?

DNA damage foci at dysfunctional telomeres

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

Association between telomere length in blood and mortality in people aged 60 years or older

Switching and signaling at the telomere

A DNA damage checkpoint response in telomere-initiated senescence

Protection of mammalian telomeres

p53 is required for radiation-induced apoptosis in mouse thymocytes

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