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Mechanism of topology simplification by type II DNA topoisomerases.

Mechanism of topology simplification by type II DNA topoisomerases.

http://www.wikidata.org/entity/Q34695074

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Synapsis of DNA ends by DNA-dependent protein kinase Structural basis for gate-DNA recognition and bending by type IIA topoisomerases Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases.Topoisomerase II, scaffold component, promotes chromatin compaction in vitro in a linker-histone H1-dependent manner Mechanisms of chiral discrimination by topoisomerase IV DNA catenation maintains structure of human metaphase chromosomes Comparison of DNA decatenation by Escherichia coli topoisomerase IV and topoisomerase III: implications for non-equilibrium topology simplification.The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks.The dynamic interplay between DNA topoisomerases and DNA topology.Simulation of DNA catenanes.DNA supercoiling and its role in DNA decatenation and unknotting.A gyrase mutant with low activity disrupts supercoiling at the replication terminus Control of the flow properties of DNA by topoisomerase II and its targeting inhibitor.Simulations of action of DNA topoisomerases to investigate boundaries and shapes of spaces of knots Computational analysis of DNA gyrase action.Braiding DNA: experiments, simulations, and models.Role of microscopic flexibility in tightly curved DNA.Topoisomerase IV bends and overtwists DNA upon binding.Inferring global topology from local juxtaposition geometry: interlinking polymer rings and ramifications for topoisomerase action How topoisomerase IV can efficiently unknot and decatenate negatively supercoiled DNA molecules without causing their torsional relaxation.Free-energy calculations for semi-flexible macromolecules: applications to DNA knotting and looping.Tightening of DNA knots by supercoiling facilitates their unknotting by type II DNA topoisomerases Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification Absence of knots in known RNA structures.How do type II topoisomerases use ATP hydrolysis to simplify DNA topology beyond equilibrium? Investigating the relaxation reaction of nonsupercoiling type II topoisomerases All tangled up: how cells direct, manage and exploit topoisomerase function.Unlinking of supercoiled DNA catenanes by type IIA topoisomerases.Local sensing of global DNA topology: from crossover geometry to type II topoisomerase processivity E. coli Gyrase Fails to Negatively Supercoil Diaminopurine-Substituted DNA.Protein-induced local DNA bends regulate global topology of recombination products Local selection rules that can determine specific pathways of DNA unknotting by type II DNA topoisomerases.Mapping the phase diagram of the writhe of DNA nanocircles using atomistic molecular dynamics simulations 3D visualization software to analyze topological outcomes of topoisomerase reactions.Local site preference rationalizes disentangling by DNA topoisomerases.DNA supercoiling inhibits DNA knotting.The role of DNA bending in type IIA topoisomerase function.Bullied no more: when and how DNA shoves proteins around.Electrostatics of DNA-DNA juxtapositions: consequences for type II topoisomerase function The why and how of DNA unlinking Theoretical models of DNA topology simplification by type IIA DNA topoisomerases

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Mechanism of topology simplification by type II DNA topoisomerases.

http://www.wikidata.org/entity/Q34695074

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2001 nî lūn-bûn

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2001 թուականի Մարտին հրատարակուած գիտական յօդուած

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2001 թվականի մարտին հրատարակված գիտական հոդված

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2001年の論文

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Mechanism of topology simplification by type II DNA topoisomerases.

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Mechanism of topology simplification by type II DNA topoisomerases.

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Mechanism of topology simplification by type II DNA topoisomerases.

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Mechanism of topology simplification by type II DNA topoisomerases.

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Mechanism of topology simplification by type II DNA topoisomerases.

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Mechanism of topology simplification by type II DNA topoisomerases.

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Mechanism of topology simplification by type II DNA topoisomerases.

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Mechanism of topology simplification by type II DNA topoisomerases.

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Mechanism of topology simplification by type II DNA topoisomerases.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Mechanism of topology simplification by type II DNA topoisomerases.

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P2093

A A Podtelezhnikov

http://www.w3.org/2001/XMLSchema#string

A V Vologodskii

http://www.w3.org/2001/XMLSchema#string

D Subramanian

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J D Griffith

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N R Cozzarelli

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V V Rybenkov

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W Zhang

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P2860

Crystal structure of the breakage-reunion domain of DNA gyrase

DNA topoisomerases

Multimerization-cyclization of DNA fragments as a method of conformational analysis.

Curved DNA: design, synthesis, and circularization.

Probability of DNA knotting and the effective diameter of the DNA double helix.

Topoisomerase II drives DNA transport by hydrolyzing one ATP

Electron microscope visualization of chromatin and other DNA-protein complexes.

DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism.

Recent developments in DNA topoisomerase II structure and mechanism.

Simplification of DNA topology below equilibrium values by type II topoisomerases.

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3045-3049

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10.1073/PNAS.061029098

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6

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98

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2001-03-01T00:00:00Z

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12084408

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11248029

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30604

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