DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin.
about
Minor groove binding of a bis-quaternary ammonium compound: the crystal structure of SN 7167 bound to d(CGCGAATTCGCG)2Substrate specificity and sequence-dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag)Development of distamycin-related DNA binding anticancer drugs.The sequence specificity of alkylation for a series of benzoic acid mustard and imidazole-containing distamycin analogues: the importance of local sequence conformation.Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.3-methyladenine-DNA-glycosylase and O6-alkyl guanine-DNA-alkyltransferase activities and sensitivity to alkylating agents in human cancer cell lines.Tallimustine in advanced previously untreated colorectal cancer, a phase II study.Effects of anticancer drugs on transcription factor-DNA interactions.DNA minor groove binding ligands: a new class of anticancer agents.Treatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitors.Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agentsSmall molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.CCAAT-box binding protein NF-Y (CBF, CP1) recognizes the minor groove and distorts DNA.Characterization of a protein recognizing minor groove binders-damaged DNA.Distamycin A and tallimustine inhibit TBP binding and basal in vitro transcription.N-methylpurine DNA glycosylase plays a pivotal role in the threshold response of ethyl methanesulfonate-induced chromosome damage.Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity.Sensitivity of CHO mutant cell lines with specific defects in nucleotide excision repair to different anti-cancer agents.Mode of action of trabectedin in myxoid liposarcomas.An overview of recent advances in duplex DNA recognition by small molecules.
P2860
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P2860
DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
DNA sequence-specific adenine ...... tard derivative of distamycin.
@ast
DNA sequence-specific adenine ...... tard derivative of distamycin.
@en
DNA sequence-specific adenine ...... tard derivative of distamycin.
@nl
type
label
DNA sequence-specific adenine ...... tard derivative of distamycin.
@ast
DNA sequence-specific adenine ...... tard derivative of distamycin.
@en
DNA sequence-specific adenine ...... tard derivative of distamycin.
@nl
prefLabel
DNA sequence-specific adenine ...... tard derivative of distamycin.
@ast
DNA sequence-specific adenine ...... tard derivative of distamycin.
@en
DNA sequence-specific adenine ...... tard derivative of distamycin.
@nl
P2093
P2860
P356
P1476
DNA sequence-specific adenine ...... tard derivative of distamycin.
@en
P2093
Broggini M
D'Incalci M
Hartley JA
Mongelli N
P2860
P356
10.1093/NAR/23.1.81
P407
P577
1995-01-01T00:00:00Z