about
DNA and the chromosome - varied targets for chemotherapySequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(CTTTTGCAAAAG)(2)The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG)Variability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2Sequence-dependent effects in drug-DNA interaction: the crystal structure of Hoechst 33258 bound to the d(CGCAAATTTGCG)2 duplexSignificance of ligand tails for interaction with the minor groove of B-DNASelective inhibition of topoisomerases from Pneumocystis carinii compared with that of topoisomerases from mammalian cellsDNA ligands as radioprotectors: molecular studies with Hoechst 33342 and Hoechst 33258.Radiation sensitization by an iodine-labelled DNA ligand.Sequence-specific interaction of Hoechst 33258 with the minor groove of an adenine-tract DNA duplex studied in solution by 1H NMR spectroscopySequence specific molecular recognition and binding by a GC recognizing Hoechst 33258 analogue to the decadeoxyribonucleotide d-[CATGGCCATG]2: structural and dynamic aspects deduced from high field 1H-NMR studies.The Hoechst 33258 covalent dimer covers a total turn of the double-stranded DNA.Topoisomerase I-mediated DNA cleavage induced by the minor groove-directed binding of bibenzimidazoles to a distal siteBinding of Hoechst 33258 and its derivatives to DNA.Hoechst 33342 induces radiosensitization in malignant glioma cells via increase in mitochondrial reactive oxygen species.Characterization of the minor groove environment in a drug-DNA complex: bisbenzimide bound to the poly[d(AT)].poly[d(AT)]duplex.Hoechst 33342 induced reactive oxygen species and impaired expression of cytochrome c oxidase subunit 1 leading to cell death in irradiated human cancer cells.Radioprotectors in radiotherapy.Origins of netropsin binding affinity and specificity: correlations of thermodynamic and structural dataDNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin.A new trinuclear complex of platinum and iron efficiently promotes cleavage of plasmid DNA.The different binding modes of Hoechst 33258 to DNA studied by electric linear dichroism.Theoretical study on binding of Hoechst 33258 with oligonucleotides.Interaction of Hoechst 33258 with repeating synthetic DNA polymers and natural DNA.'SPKK' motifs prefer to bind to DNA at A/T-rich sites.Studies on the interaction of the food colorant tartrazine with double stranded deoxyribonucleic acid.DNA-sequence specific recognition by a thiazole analogue of netropsin: a comparative footprinting study.Non-covalent DNA groove-binding by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.Spectroscopic and microcalorimetric studies on the molecular binding of food colorant acid red 27 with deoxyribonucleic acid.High resolution footprinting of EcoRI and distamycin with Rh(phi)2(bpy)3+, a new photofootprinting reagent.Sequence-directed curvature of repetitive AluI DNA in constitutive heterochromatin of Artemia franciscanaQuantum chemical studies employing an ab initio combination approach on the binding of the bis-benzimidazole Hoechst 33258 to the minor groove of DNA.DNA sequence preferences of several AT-selective minor groove binding ligandsMode of DNA binding of bis-benzimidazoles and related structures studied by electric linear dichroism.Theoretical studies using an ab initio and molecular modelling combination method on the binding of sequence recognition altered bis-benzimidazoles to the minor groove of DNA.Interaction of minor groove binding ligands with long AT tractsMultimode interaction of Hoechst 33258 with eukaryotic DNA; quantitative analysis of the DNA conformational changes.Theoretical studies employing an ab initio and molecular modeling combination method on the DNA binding of bis-benzimidazoles designed for bioreductive activation.Ultraviolet light-induced cleavage of DNA in the presence of iodoHoechst 33258: the sequence specificity of the reaction.Quantitative footprinting analysis of the netropsin-DNA interaction.
P2860
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P2860
description
1985 nî lūn-bûn
@nan
1985 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Molecular recognition of B-DNA by Hoechst 33258.
@ast
Molecular recognition of B-DNA by Hoechst 33258.
@en
type
label
Molecular recognition of B-DNA by Hoechst 33258.
@ast
Molecular recognition of B-DNA by Hoechst 33258.
@en
prefLabel
Molecular recognition of B-DNA by Hoechst 33258.
@ast
Molecular recognition of B-DNA by Hoechst 33258.
@en
P2860
P356
P1476
Molecular recognition of B-DNA by Hoechst 33258.
@en
P2093
Harshman KD
P2860
P304
P356
10.1093/NAR/13.13.4825
P407
P577
1985-07-01T00:00:00Z