Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity.

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Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.Brostallicin (PNU-166196), a new minor groove DNA binder: preclinical and clinical activity.

P2860

Q36671252-98715836-6D9A-424F-A0A3-19B2E864E12C Q43235606-52C7A839-7032-4377-8F51-FA519ECEE9F0

P2860

Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity.

Item

http://www.wikidata.org/entity/Q40949673

description

1999 nî lūn-bûn

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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1999年论文

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1999年论文

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name

Alpha-bromoacryloyl derivative ...... with antineoplastic activity.

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type

Item

label

Alpha-bromoacryloyl derivative ...... with antineoplastic activity.

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Alpha-bromoacryloyl derivative ...... with antineoplastic activity.

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P1476

Alpha-bromoacryloyl derivative ...... r with antineoplastic activity

@en

P2093

Cirò M

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Cozzi P

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Gallinari F

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Geroni C

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P2860

DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.

Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue.

DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin.

Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53

Estimation of the haematological toxicity of minor groove alkylators using tests on human cord blood cells

DNA minor groove binding ligands: a new class of anticancer agents.

Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53.

DNA sequence specificity of antitumor agents. Oncogenes as possible targets for cancer therapy.

Measurement of the sequence specificity of covalent DNA modification by antineoplastic agents using Taq DNA polymerase

Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis.

P2888

sj.bjc.6690453

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991-997

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scholarly article

P356

10.1038/SJ.BJC.6690453

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English

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P478

http://www.w3.org/2001/XMLSchema#string

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Maurizio D'Incalci

Sergio Marchini

Massimo Broggini

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1999-06-01T00:00:00Z

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12937085

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10362106

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2363030

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Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity.

about

P2860

P2860

Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932