about
Rule-based cell systems model of aging using feedback loop motifs mediated by stress responsesTP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephantsSenescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressorMutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program.p53, sex, and aging: lessons from the fruit fly.It's all about balance: p53 and agingTranscription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene.Pathologies associated with the p53 response.p53 and ARF: unexpected players in autophagy.Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3Trade-offs between cancer and other diseases: do they exist and influence longevity?Dynamic energy budget approaches for modelling organismal ageing.Tumor suppression and normal aging in mice with constitutively high p53 activity.Telomeres and aging.Inflammation and p53: A Tale of Two StressesInvited review: Theories of aging.The impact of altered p53 dosage on hematopoietic stem cell dynamics during agingNovel protein-protein interactions of TPPII, p53, and SIRT7.Opposite phenotypes of cancer and aging arise from alternative regulation of common signaling pathways.Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform.The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging.Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.Therapeutic targeting of the p53 pathway in cancer stem cells.Permanent embryo arrest: molecular and cellular concepts.MDM2-A, a common Mdm2 splice variant, causes perinatal lethality, reduced longevity and enhanced senescence.Aging stem cells, latexin, and longevity.Trade-off between cancer and aging: what role do other diseases play? Evidence from experimental and human population studies.The consequence of oncomorphic TP53 mutations in ovarian cancer.Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging.Anticipating anticipation: pursuing identification of cardiomyocyte circadian clock function.Cancer: A disease at the crossroads of trade-offs.Age-related Deterioration of Hematopoietic Stem Cells.p53 and the Carcinogenicity of Chronic Inflammation.GSK3 and p53 - is there a link in Alzheimer's disease?Replicative senescence enhances apoptosis induced by pemphigus autoimmune antibodies in human keratinocytes.Checkpoint genes, ageing, and the development of cancer.Simulation of Cellular Energy Restriction in Quiescence (ERiQ)-A Theoretical Model for Aging.A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models.Early life exposure to the 1918 influenza pandemic and old-age mortality by cause of death
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Does p53 affect organismal aging?
@ast
Does p53 affect organismal aging?
@en
Does p53 affect organismal aging?
@nl
type
label
Does p53 affect organismal aging?
@ast
Does p53 affect organismal aging?
@en
Does p53 affect organismal aging?
@nl
prefLabel
Does p53 affect organismal aging?
@ast
Does p53 affect organismal aging?
@en
Does p53 affect organismal aging?
@nl
P2860
P356
P1476
Does p53 affect organismal aging?
@en
P2093
Lawrence A Donehower
P2860
P356
10.1002/JCP.10104
P577
2002-07-01T00:00:00Z