CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells - Wikidata - wikimedia - TriplyDB

CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells

CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells

http://www.wikidata.org/entity/Q34772159

about

Intercellular transfer of oncogenic H-Ras at the immunological synapse An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells Lysosome-Related Effector Vesicles in T Lymphocytes and NK Cells Cell biological steps and checkpoints in accessing NK cell cytotoxicity Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse.Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment.Rapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling Overcoming chemoresistance of small-cell lung cancer through stepwise HER2-targeted antibody-dependent cell-mediated cytotoxicity and VEGF-targeted antiangiogenesis.Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells.Navigating barriers: the challenge of directed secretion at the natural killer cell lytic immunological synapse.Shouts, whispers and the kiss of death: directional secretion in T cells Cdc42-mediated MTOC polarization in dendritic cells controls targeted delivery of cytokines at the immune synapse.Substance P inhibits natural killer cell cytotoxicity through the neurokinin-1 receptor.The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope Many NK cell receptors activate ERK2 and JNK1 to trigger microtubule organizing center and granule polarization and cytotoxicity.Granzyme B- and Fas ligand-mediated cytotoxic function induced by mitogenic CD28 stimulation of human memory CD4+ T cells Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse.Human NK cell lytic granules and regulation of their exocytosis JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity Functional insights on the polarized redistribution of leukocyte integrins and their ligands during leukocyte migration and immune interactions.A peptide antagonist disrupts NK cell inhibitory synapse formation The human 2B4 and NTB-A receptors bind the influenza viral hemagglutinin and co-stimulate NK cell cytotoxicity.Contrasting effects of anti-Ly49A due to MHC class I cis binding on NK cell-mediated allogeneic bone marrow cell resistance.The killer's kiss: the many functions of NK cell immunological synapses.LFA-1 and CD2 synergize for the Erk1/2 activation in the Natural Killer (NK) cell immunological synapse.Formation and function of the lytic NK-cell immunological synapse.SHP-2 expression negatively regulates NK cell function.The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse.Altered functions of alveolar macrophages and NK cells involved in asbestos-related diseases.The central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse.Activation of Lymphocyte Cytolytic Machinery: Where are We?IQGAP1: insights into the function of a molecular puppeteer.The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells.Important role for NKp30 in synapse formation and activation of NK cells.IQGAP1 involvement in MTOC and granule polarization in NK-cell cytotoxicity.Decrease in phosphorylation of ERK following decreased expression of NK cell-activating receptors in human NK cell line exposed to asbestos.The mitogen-activated protein kinase scaffold KSR1 is required for recruitment of extracellular signal-regulated kinase to the immunological synapse.PPP1R9B (Neurabin 2): involvement and dynamics in the NK immunological synapse.

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P2860

CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells

http://www.wikidata.org/entity/Q34772159

description

2006 nî lūn-bûn

@nan

2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

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2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@ast

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@en

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@nl

type

label

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@ast

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@en

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@nl

prefLabel

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@ast

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@en

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@nl

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PNAS.0604236103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

CD28-stimulated ERK2 phosphory ...... r and granules in YTS NK cells

@en

P2093

Baoxue Ge

http://www.w3.org/2001/XMLSchema#string

David S J Allan

http://www.w3.org/2001/XMLSchema#string

Hernan Kopcow

http://www.w3.org/2001/XMLSchema#string

Jack L Strominger

http://www.w3.org/2001/XMLSchema#string

Konrad Krzewski

http://www.w3.org/2001/XMLSchema#string

Xi Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells

Human decidual NK cells form immature activating synapses and are not cytotoxic.

Innate immune recognition

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

A view to a kill: signals triggering cytotoxicity

The MAPK signaling cascade

Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: identification of perforin and granzyme B mobilization by functional ERK2.

Stepwise cytoskeletal polarization as a series of checkpoints in innate but not adaptive cytolytic killing.

DCX, a new mediator of the JNK pathway.

Signaling through integrin LFA-1 leads to filamentous actin polymerization and remodeling, resulting in enhanced T cell adhesion.

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27

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103

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6982236

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16801532

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phosphorylation

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1502460

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