RNF43 is frequently mutated in colorectal and endometrial cancers - Wikidata - wikimedia - TriplyDB

RNF43 is frequently mutated in colorectal and endometrial cancers

RNF43 is frequently mutated in colorectal and endometrial cancers

http://www.wikidata.org/entity/Q34817306

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Wnt Signaling in Cancer Stem Cell Biology Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer Ubiquitin proteasome system research in gastrointestinal cancer New therapeutic strategies for BRAF mutant colorectal cancers Genetics of the serrated pathway to colorectal cancer Integrative clinical genomics of advanced prostate cancer.Dysregulation of ubiquitin ligases in cancer Proceedings of the third international molecular pathological epidemiology (MPE) meeting.Genomic profiling reveals mutational landscape in parathyroid carcinomas Patients with genetically heterogeneous synchronous colorectal cancer carry rare damaging germline mutations in immune-related genes.Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding.Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer.Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1 R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine Moving upstream in the war on WNTs.Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy.Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid-type fibromatosis by whole-exome sequencing and genomic analysis.Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer Structural analysis of tumor-related single amino acid mutations in human MxA protein SNooPer: a machine learning-based method for somatic variant identification from low-pass next-generation sequencing.Wnt addiction of genetically defined cancers reversed by PORCN inhibition.A deleterious RNF43 germline mutation in a severely affected serrated polyposis kindred.Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma Wnt pathway activation by ADP-ribosylation.A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC.The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis.MonoSeq Variant Caller Reveals Novel Mononucleotide Run Indel Mutations in Tumors with Defective DNA Mismatch Repair The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma.Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling.Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer.RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.Association mining of mutated cancer genes in different clinical stages across 11 cancer types Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure.Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms.Targeting the WNT Signaling Pathway in Cancer Therapeutics.Precision medicine in colorectal cancer: evolving genomic landscape and emerging consensus.Gene mutations in gastric cancer: a review of recent next-generation sequencing studies.RNF183 promotes proliferation and metastasis of colorectal cancer cells via activation of NF-κB-IL-8 axis.

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RNF43 is frequently mutated in colorectal and endometrial cancers

http://www.wikidata.org/entity/Q34817306

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2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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name

RNF43 is frequently mutated in colorectal and endometrial cancers

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RNF43 is frequently mutated in colorectal and endometrial cancers

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RNF43 is frequently mutated in colorectal and endometrial cancers

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type

label

RNF43 is frequently mutated in colorectal and endometrial cancers

@ast

RNF43 is frequently mutated in colorectal and endometrial cancers

@en

RNF43 is frequently mutated in colorectal and endometrial cancers

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prefLabel

RNF43 is frequently mutated in colorectal and endometrial cancers

@ast

RNF43 is frequently mutated in colorectal and endometrial cancers

@en

RNF43 is frequently mutated in colorectal and endometrial cancers

@nl

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Nature Genetics

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RNF43 is frequently mutated in colorectal and endometrial cancers

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Eliezer M Van Allen

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Eran Hodis

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Mai Yamauchi

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Marios Giannakis

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Michael S Lawrence

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Reiko Nishihara

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Shuji Ogino

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William C Hahn

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Xinmeng Jasmine Mu

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Zhi Rong Qian

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P2860

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

A landscape of driver mutations in melanoma

Comprehensive molecular characterization of human colon and rectal cancer

Comprehensive molecular portraits of human breast tumours

Wnt/β-catenin signaling and disease

TopHat-Fusion: an algorithm for discovery of novel fusion transcripts

Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.

Comprehensive molecular characterization of gastric adenocarcinoma

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival

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1264-1266

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10.1038/NG.3127

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12

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46

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Kristian Cibulskis

Joseph Rosenbluh

Charles S. Fuchs

Levi A Garraway

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2014-10-26T00:00:00Z

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267744040

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25344691

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4283570

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