In vivo generation of highly abundant sequence-specific oligonucleotides for antisense and triplex gene regulation
about
Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAsTherapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesRNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cellsThe expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization.Improved accumulation and activity of ribozymes expressed from a tRNA-based RNA polymerase III promoter.RNA aptamers as effective protein antagonists in a multicellular organism.Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesionHyperstable U1snRNA complementary to the K-ras transcripts induces cell death in pancreatic cancer cells.Viral Vector-Mediated Antisense Therapy for Genetic Diseases.Intracellular generation of single-stranded DNA for chromosomal triplex formation and induced recombination.Efficient hammerhead ribozyme-mediated cleavage of the structured hepatitis B virus encapsidation signal in vitro and in cell extracts, but not in intact cells.Ribozyme inhibition of alphavirus replication.TGF-alpha antisense gene therapy inhibits head and neck squamous cell carcinoma growth in vivo.Evidence of post-transcriptional regulation of U6 small nuclear RNA.Colocalization of antisense RNAs and ribozymes with their target mRNAs.Inhibition of human non-small cell lung tumors by a c-Met antisense/U6 expression plasmid strategy.Lack of toxicity of EGFR antisense gene therapy.Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter.
P2860
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P2860
In vivo generation of highly abundant sequence-specific oligonucleotides for antisense and triplex gene regulation
description
1994 nî lūn-bûn
@nan
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
name
In vivo generation of highly a ...... se and triplex gene regulation
@ast
In vivo generation of highly a ...... se and triplex gene regulation
@en
In vivo generation of highly a ...... se and triplex gene regulation
@nl
type
label
In vivo generation of highly a ...... se and triplex gene regulation
@ast
In vivo generation of highly a ...... se and triplex gene regulation
@en
In vivo generation of highly a ...... se and triplex gene regulation
@nl
prefLabel
In vivo generation of highly a ...... se and triplex gene regulation
@ast
In vivo generation of highly a ...... se and triplex gene regulation
@en
In vivo generation of highly a ...... se and triplex gene regulation
@nl
P2093
P2860
P356
P1476
In vivo generation of highly a ...... se and triplex gene regulation
@en
P2093
P2860
P304
P356
10.1093/NAR/22.14.2830
P407
P577
1994-07-01T00:00:00Z