DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair.
about
Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cellsInteraction of human Ku70 with TRF2Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complexKARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity.Nonhomologous end joining and V(D)J recombination require an additional factorThe C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunitSaccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathwaysGene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1DChk2 phosphorylation of BRCA1 regulates DNA double-strand break repairDeficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joiningSignificant correlation of species longevity with DNA double strand break recognition but not with telomere lengthAutophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks.Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.Ubiquitylation, neddylation and the DNA damage responseThe catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cellsKu70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombinationThe XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinaseMechanistic constraints on diversity in human V(D)J recombinationInteraction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acidsMolecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20Positive regulation of DNA double strand break repair activity during differentiation of long life span cells: the example of adipogenesisBoth V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination.Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.SCID dogs: similar transplant potential but distinct intra-uterine growth defects and premature replicative senescence compared with SCID mice.DNA damage responses in human induced pluripotent stem cells and embryonic stem cells.Prospects for the precise engineering of plant genomes by homologous recombination.Modulation of Sp1 phosphorylation by human immunodeficiency virus type 1 Tat.Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus.DNA binding by the KP repressor protein inhibits P-element transposase activity in vitro.Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins.Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoiningThe p53 response to DNA damage in vivo is independent of DNA-dependent protein kinaseThe DNA-damage response: new molecular insights and new approaches to cancer therapyDNA-PK-dependent binding of DNA ends to plasmids containing nuclear matrix attachment region DNA sequences: evidence for assembly of a repair complex.A single amino acid substitution in DNA-PKcs explains the novel phenotype of the CHO mutant, XR-C2.Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.Combination immunotherapy: a road map.Radiation-induced chromosome aberrations in Saccharomyces cerevisiae: influence of DNA repair pathways.A central region of Ku80 mediates interaction with Ku70 in vivo.
P2860
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P2860
DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
DNA-dependent protein kinase a ...... NA double-strand break repair.
@ast
DNA-dependent protein kinase a ...... NA double-strand break repair.
@en
DNA-dependent protein kinase a ...... NA double-strand break repair.
@nl
type
label
DNA-dependent protein kinase a ...... NA double-strand break repair.
@ast
DNA-dependent protein kinase a ...... NA double-strand break repair.
@en
DNA-dependent protein kinase a ...... NA double-strand break repair.
@nl
prefLabel
DNA-dependent protein kinase a ...... NA double-strand break repair.
@ast
DNA-dependent protein kinase a ...... NA double-strand break repair.
@en
DNA-dependent protein kinase a ...... NA double-strand break repair.
@nl
P2093
P2860
P356
P1476
DNA-dependent protein kinase a ...... NA double-strand break repair.
@en
P2093
N J Finnie
S P Jackson
T M Gottlieb
P2860
P304
P356
10.1073/PNAS.92.1.320
P407
P577
1995-01-01T00:00:00Z