Human interferon-lambda3 is a potent member of the type III interferon family. - Wikidata - wikimedia - TriplyDB

Human interferon-lambda3 is a potent member of the type III interferon family.

Human interferon-lambda3 is a potent member of the type III interferon family.

http://www.wikidata.org/entity/Q34873799

about

Evolutionary divergence and functions of the human interleukin (IL) gene family Interferon lambda: a new sword in cancer immunotherapy Genetic variation in IL28B and spontaneous clearance of hepatitis C virus Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques Interferon-λ: Immune Functions at Barrier Surfaces and Beyond Genetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactions Comparison of antiviral activity of lambda-interferons against HIV replication in macrophages Interferon- Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family Crystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1 Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates Interferon-lambdas: the modulators of antivirus, antitumor, and immune responses Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines Pandemic H1N1 2009 influenza A virus induces weak cytokine responses in human macrophages and dendritic cells and is highly sensitive to the antiviral actions of interferons.Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ribavirin therapy in chronic hepatitis C patients.Polymorphisms of T helper cell cytokine-associated genes and survival of hemodialysis patients - a prospective study.Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus.The association between interleukin-28B gene polymorphisms as a potential biomarker and the risk of chronic Periodontitis in an Iranian population.The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs.Interferon lambda: opportunities, risks, and uncertainties in the fight against HCV.IFN-λ4: the paradoxical new member of the interferon lambda family.Interferon-λ1 linked to a stabilized dimer of Fab potently enhances both antitumor and antiviral activities in targeted cells.IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway.IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-α plus ribavirin therapy in Taiwanese chronic HCV infection.The impact of interferon lambda 3 gene polymorphism on natural course and treatment of hepatitis C Design and evaluation of novel interferon lambda analogs with enhanced antiviral activity and improved drug attributes.Interferon-lambda (IFN-λ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes.Antiviral Activities of Different Interferon Types and Subtypes against Hepatitis E Virus Replication.IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes.Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines.Pharmacogenomics of chronic hepatitis C therapy with genome-wide association studies.STAT2: A shape-shifting anti-viral super STAT Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses Interferon lambda 4 expression is suppressed by the host during viral infection.Dynamic expression profiling of type I and type III interferon-stimulated hepatocytes reveals a stable hierarchy of gene expression Interferon Lambda: Modulating Immunity in Infectious Diseases.IL28B and the control of hepatitis C virus infection.Assessing gene-gene interactions in pharmacogenomics.IFN-λ and IgE-mediated allergic disease: a potential future role?The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.

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P2860

Human interferon-lambda3 is a potent member of the type III interferon family.

http://www.wikidata.org/entity/Q34873799

description

2008 nî lūn-bûn

@nan

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Human interferon-lambda3 is a potent member of the type III interferon family.

@ast

Human interferon-lambda3 is a potent member of the type III interferon family.

@en

Human interferon-lambda3 is a potent member of the type III interferon family.

@nl

type

label

Human interferon-lambda3 is a potent member of the type III interferon family.

@ast

Human interferon-lambda3 is a potent member of the type III interferon family.

@en

Human interferon-lambda3 is a potent member of the type III interferon family.

@nl

prefLabel

Human interferon-lambda3 is a potent member of the type III interferon family.

@ast

Human interferon-lambda3 is a potent member of the type III interferon family.

@en

Human interferon-lambda3 is a potent member of the type III interferon family.

@nl

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P1433

Genes and Immunity

P1476

Human interferon-lambda3 is a potent member of the type III interferon family

@en

P2093

J Melchjorsen

http://www.w3.org/2001/XMLSchema#string

O J Hamming

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P2860

Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling

Biological activity of interleukins-28 and -29: comparison with type I interferons

IL-28, IL-29 and their class II cytokine receptor IL-28R

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

How cells respond to interferons

Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma

Interferons, immunity and cancer immunoediting

Modulation of the human cytokine response by interferon lambda-1 (IFN-lambda1/IL-29)

Interferons, interferon-like cytokines, and their receptors

IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo.

P2888

P304

125-131

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scholarly article

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10.1038/GENE.2008.87

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2

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P478

10

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Hans Henrik Gad

Christoffer Dellgren

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2008-11-06T00:00:00Z

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23454863

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1003925481

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18987645

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