Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals - Wikidata - wikimedia - TriplyDB

Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals

Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals

http://www.wikidata.org/entity/Q34907871

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Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases Lipidomics reveals a remarkable diversity of lipids in human plasma Mycotoxins and human disease: a largely ignored global health issue 1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma Sphingolipid signaling in metabolic disorders The External Aldimine Form of Serine Palmitoyltransferase: STRUCTURAL, KINETIC, AND SPECTROSCOPIC ANALYSIS OF THE WILD-TYPE ENZYME AND HSAN1 MUTANT MIMICS Lipidomics for studying metabolism HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship.Elucidating the chemical structure of native 1-deoxysphingosine.An introduction to sphingolipid metabolism and analysis by new technologies Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids.Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation.A disease-causing mutation in the active site of serine palmitoyltransferase causes catalytic promiscuity Deoxysphingoid bases as plasma markers in diabetes mellitus.Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1.Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction Biophysical properties of novel 1-deoxy-(dihydro)ceramides occurring in mammalian cells Altered sphingoid base profiles in type 1 compared to type 2 diabetes.Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells Novel HSAN1 mutation in serine palmitoyltransferase resides at a putative phosphorylation site that is involved in regulating substrate specificity Biomarkers of NAFLD progression: a lipidomics approach to an epidemic.Sphingosine-1-phosphate receptor 2 Many ceramides.Plasma 1-deoxysphingolipids are predictive biomarkers for type 2 diabetes mellitus Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Analysis of mammalian sphingolipids by liquid chromatography tandem mass spectrometry (LC-MS/MS) and tissue imaging mass spectrometry (TIMS).Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system.L-Serine Deficiency Elicits Intracellular Accumulation of Cytotoxic Deoxysphingolipids and Lipid Body Formation.Open Field Study of Some Zea mays Hybrids, Lipid Compounds and Fumonisins Accumulation.Substrate Availability of Mutant SPT Alters Neuronal Branching and Growth Cone Dynamics in Dorsal Root Ganglia Characterization of mutant serine palmitoyltransferase 1 in LY-B cells.Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons.Sphingolipids: regulators of crosstalk between apoptosis and autophagy Hereditary sensory and autonomic neuropathy type 1 (HSANI) caused by a novel mutation in SPTLC2.Elevated Nuclear and Cytoplasmic FTY720-Phosphate in Mouse Embryonic Fibroblasts Suggests the Potential for Multiple Mechanisms in FTY720-Induced Neural Tube Defects.The interplay between bioactive sphingolipids and steroid hormones.Sphingolipids: the nexus between Gaucher disease and insulin resistance.Structural, mechanistic and regulatory studies of serine palmitoyltransferase.Fumonisins in plant-origin food and fodder--a review.

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P2860

Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals

http://www.wikidata.org/entity/Q34907871

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2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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Ceramide synthase inhibition b ...... mmalian cell lines and animals

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Ceramide synthase inhibition b ...... mmalian cell lines and animals

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Ceramide synthase inhibition b ...... mmalian cell lines and animals

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Journal of Biological Chemistry

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Ceramide synthase inhibition b ...... mmalian cell lines and animals

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Alfred H Merrill

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Elaine Wang

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Ethel C Garnier-Amblard

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Genevieve S Bondy

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Hyejung Park

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Kenneth A Voss

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Lanny S Liebeskind

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M Cameron Sullards

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Nicholas C Zitomer

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Ronald T Riley

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P2860

Protein measurement with the Folin phenol reagent

Discovery and occurrence of the fumonisins: a historical perspective

Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins.

Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis.

An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme

Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin

Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols.

Differential sensitivity of rat kidney and liver to fumonisin toxicity: organ-specific differences in toxin accumulation and sphingoid base metabolism.

When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis.

Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics.

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4786-4795

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scholarly article

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10.1074/JBC.M808798200

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8

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284

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2008-12-18T00:00:00Z

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23676603

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19095642

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1-deoxymethylsphinganine(1+)

1-deoxysphinganine(1+)

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2643501

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