Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors. - Wikidata - wikimedia - TriplyDB

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

http://www.wikidata.org/entity/Q34909737

about

Anergic B Cells: Precarious On-Call Warriors at the Nexus of Autoimmunity and False-Flagged Pathogens Microparticles That Form Immune Complexes as Modulatory Structures in Autoimmune Responses The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy Immunological aspects in chronic lymphocytic leukemia (CLL) development To B or not to B cells-mediate a healthy start to life New insights into the enigma of immunoglobulin D.Immune history profoundly affects broadly protective B cell responses to influenza.Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection.Self-organized criticality theory of autoimmunity Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.Bruton's tyrosine kinase promotes persistence of mature anti-insulin B cells.B cells and type 1 diabetes ...in mice and men.B cell receptor signaling-based index as a biomarker for the loss of peripheral immune tolerance in autoreactive B cells in rheumatoid arthritis.Collapse of the CD27+ B-cell compartment associated with systemic plasmacytosis in patients with advanced melanoma and other cancers Memory B cell subsets and plasmablasts are lower in early than in long-standing rheumatoid arthritis.Non-MHC antigenic targets of the humoral immune response in transplantation Molecular underpinning of B-cell anergy.Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen.The function and regulation of immunoglobulin D.Harnessing the immune system's arsenal: producing human monoclonal antibodies for therapeutics and investigating immune responses.An entity evolving into a community: defining the common ancestor and evolutionary trajectory of chronic lymphocytic leukemia stereotyped subset #4.Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients.High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones Innate pathways to B-cell activation and tolerance.Endogenous antigen tunes the responsiveness of naive B cells but not T cells Antigen-specific suppression of humoral immunity by anergic Ars/A1 B cells.Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen.Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes.Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity Tolerant anti-insulin B cells are effective APCs Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells.Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant.Antigen nature and complexity influence human antibody light chain usage and specificity.Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization.Temporal dynamics of clonal evolution in chronic lymphocytic leukemia with stereotyped IGHV4-34/IGKV2-30 antigen receptors: longitudinal immunogenetic evidence.Molecular basis of 9G4 B cell autoreactivity in human systemic lupus erythematosus IgD attenuates the IgM-induced anergy response in transitional and mature B cells.Functionally responsive self-reactive B cells of low affinity express reduced levels of surface IgM.Mouse models of systemic lupus erythematosus reveal a complex pathogenesis.

P2860

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P2860

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

http://www.wikidata.org/entity/Q34909737

description

2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Functional anergy in a subpopu ...... tive immunoglobulin receptors.

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Functional anergy in a subpopu ...... tive immunoglobulin receptors.

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Functional anergy in a subpopu ...... tive immunoglobulin receptors.

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Journal of Experimental Medicine

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Functional anergy in a subpopu ...... ctive immunoglobulin receptors

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P2093

A Darise Farris

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Britt Nakken

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Christina Helms

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Kenneth Smith

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Kristi A Koelsch

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Lori Garman

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Melissa Mathias

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Mike Swiatkowski

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Nai-Ying Zheng

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Patrick C Wilson

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P2860

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes

Clues to the etiology of autoimmune diseases through analysis of immunoglobulin genes.

A modification of Jerne's theory of antibody production using the concept of clonal selection

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

Predominant autoantibody production by early human B cell precursors

Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive.

Atypical VH-D-JH rearrangements in newborn autoimmune MRL mice.

Anergy and not clonal ignorance determines the fate of B cells that recognize a physiological autoantigen.

Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes.

P304

139-151

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10.1084/JEM.20080611

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1

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206

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2008-12-22T00:00:00Z

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23685485

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19103878

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2626668

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