Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive.
about
Somatic mutagenesis in autoimmunityThe outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergyEndocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells.Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease.Augmented B lymphocyte response to antigen in the absence of antigen-induced B lymphocyte signaling in an IgG-transgenic mouse lineReceptor editing in peripheral B cell tolerance.Modulation of in vitro murine B-lymphocyte response by curcuminGerminal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.Central B-cell tolerance: where selection begins.Molecular underpinning of B-cell anergy.Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing.Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.Excessive amounts of mu heavy chain block B-cell developmentMonophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy.Macrophages prevent the differentiation of autoreactive B cells by secreting CD40 ligand and interleukin-6Megakaryocyte progenitors are the main APCs inducing Th17 response to lupus autoantigens and foreign antigensAutoreactive preplasma cells break tolerance in the absence of regulation by dendritic cells and macrophagesCellular and genetic mechanisms of self tolerance and autoimmunity.Retention of anergy and inhibition of antibody responses during acute γ herpesvirus 68 infectionEndogenous antigen tunes the responsiveness of naive B cells but not T cellsLoss of the proapoptotic protein, Bim, breaks B cell anergyEssential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kappa B in B cell clonal anergy.Immunogenicity of Isogenic IgG in Aggregates and Immune Complexes.Receptor cross-talk spatially restricts p-ERK during TLR4 stimulation of autoreactive B cells.Antigen-specific suppression of humoral immunity by anergic Ars/A1 B cells.Activation and tolerance in CD4(+) T cells reactive to an immunoglobulin variable region.Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivityContinuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells.B-cell anergy: from transgenic models to naturally occurring anergic B cells?Multiple paths to loss of anergy and gain of autoimmunity.Low-affinity, Smith antigen-specific B cells are tolerized by dendritic cells and macrophages.Transmodulation of BCR signaling by transduction-incompetent antigen receptors: implications for impaired signaling in anergic B cellsA new site-directed transgenic rheumatoid factor mouse model demonstrates extrafollicular class switch and plasmablast formationB cells and immunological tolerance.Functional silencing is initiated and maintained in immature anti-insulin B cellsContinual signaling is responsible for constitutive ERK phosphorylation in B-1a cells.IgD attenuates the IgM-induced anergy response in transitional and mature B cells.Anti-CD79 antibody induces B cell anergy that protects against autoimmunity.Functionally responsive self-reactive B cells of low affinity express reduced levels of surface IgM.Receptors, subcellular compartments and the regulation of peripheral B cell responses: the illuminating state of anergy.
P2860
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P2860
Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Activation and anergy in bone ...... ten specific and autoreactive.
@ast
Activation and anergy in bone ...... ten specific and autoreactive.
@en
type
label
Activation and anergy in bone ...... ten specific and autoreactive.
@ast
Activation and anergy in bone ...... ten specific and autoreactive.
@en
prefLabel
Activation and anergy in bone ...... ten specific and autoreactive.
@ast
Activation and anergy in bone ...... ten specific and autoreactive.
@en
P2093
P1433
P1476
Activation and anergy in bone ...... pten specific and autoreactive
@en
P2093
P356
10.1016/S1074-7613(01)00087-5
P407
P50
P577
2001-01-01T00:00:00Z