Mechanically activated integrin switch controls alpha5beta1 function.
about
Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectinAnalysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturationIntegrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesionsProteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motilityFeedback amplification of fibrosis through matrix stiffening and COX-2 suppressionAction and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseFibronectin Mechanobiology Regulates TumorigenesisMechanosensing via cell-matrix adhesions in 3D microenvironmentsFocal adhesions, stress fibers and mechanical tensionNon-muscle myosin II in disease: mechanisms and therapeutic opportunitiesMechanochemical regulation of growth cone motilityMechanosensitivity and compositional dynamics of cell-matrix adhesionsInsidious changes in stromal matrix fuel cancer progressionMechanobiology of myofibroblast adhesion in fibrotic cardiac diseaseMechanical regulation of T-cell functionsOsteocytes: master orchestrators of boneTumor cell migration in complex microenvironmentsRole of Mechanical Cues in Cell Differentiation and Proliferation: A 3D Numerical ModelCation type specific cell remodeling regulates attachment strengthMolecular dynamics simulations of forced unbending of integrin α(v)β₃Cancer cell invasion is enhanced by applied mechanical stimulationStructural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet TwistingAtomic Basis for the Species-specific Inhibition of V Integrins by Monoclonal Antibody 17E6 Is Revealed by the Crystal Structure of V 3 Ectodomain-17E6 Fab ComplexBiology and structure of leukocyte β 2 integrins and their role in inflammationTumor-induced solid stress activates β-catenin signaling to drive malignant behavior in normal, tumor-adjacent cellsNon-muscle myosin II takes centre stage in cell adhesion and migrationIntegrin clustering is driven by mechanical resistance from the glycocalyx and the substrateVisualization of Src and FAK activity during the differentiation process from HMSCs to osteoblastsMyosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progressionCell adhesion: integrating cytoskeletal dynamics and cellular tension.A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling.Activation of beta 1 but not beta 3 integrin increases cell traction forces.Integrins in cell migrationFibronectins, their fibrillogenesis, and in vivo functions.Integrins and extracellular matrix in mechanotransductionMechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.Spatiotemporal organization, regulation, and functions of tractions during neutrophil chemotaxis.Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells
P2860
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P2860
Mechanically activated integrin switch controls alpha5beta1 function.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mechanically activated integrin switch controls alpha5beta1 function.
@ast
Mechanically activated integrin switch controls alpha5beta1 function.
@en
Mechanically activated integrin switch controls alpha5beta1 function.
@nl
type
label
Mechanically activated integrin switch controls alpha5beta1 function.
@ast
Mechanically activated integrin switch controls alpha5beta1 function.
@en
Mechanically activated integrin switch controls alpha5beta1 function.
@nl
prefLabel
Mechanically activated integrin switch controls alpha5beta1 function.
@ast
Mechanically activated integrin switch controls alpha5beta1 function.
@en
Mechanically activated integrin switch controls alpha5beta1 function.
@nl
P2093
P356
P1433
P1476
Mechanically activated integrin switch controls alpha5beta1 function.
@en
P2093
David Boettiger
Julie C Friedland
Mark H Lee
P304
P356
10.1126/SCIENCE.1168441
P407
P577
2009-01-01T00:00:00Z