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Angiopoietin-2 is critical for cytokine-induced vascular leakage

Angiopoietin-2 is critical for cytokine-induced vascular leakage

http://www.wikidata.org/entity/Q34935131

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Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling.Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury.Low Serum Angiopoietin-1, High Serum Angiopoietin-2, and High Ang-2/Ang-1 Protein Ratio are Associated with Early Onset Sepsis in Surinamese Newborns.KLF2 and KLF4 control endothelial identity and vascular integrity Plastic roles of pericytes in the blood-retinal barrier.Plasma angiopoietin-2 outperforms other markers of endothelial injury in prognosticating pediatric ARDS mortality.Endothelial destabilization by angiopoietin-2 via integrin β1 activation.Granulocyte/macrophage colony-stimulating factor influences angiogenesis by regulating the coordinated expression of VEGF and the Ang/Tie system.Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice.CSF Levels of Angiopoietin-2 Do Not Differ between Patients with CSF Fluid Leakage Syndrome and Controls.Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes.Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.Synergistic actions of blocking angiopoietin-2 and tumor necrosis factor-α in suppressing remodeling of blood vessels and lymphatics in airway inflammation VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread.Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation Platelets regulate vascular endothelial stability: assessing the storage lesion and donor variability of apheresis platelets.Intramyocardial haemorrhage after acute myocardial infarction.Angiogenesis in malignant melanoma.The Angiopoietin-Tie2 Signaling Axis in Systemic Inflammation.The anti-angiogenic effect of dexamethasone in a murine hepatocellular carcinoma model by augmentation of gluconeogenesis pathway in malignant cells.Endothelial glycocalyx breakdown is mediated by angiopoietin-2.Pericytes of the neurovascular unit: key functions and signaling pathways.Visualization of endothelial barrier damage prior to formation of atherosclerotic plaques.Therapeutic targeting of the angiopoietin-TIE pathway.Angiopoietin-2 mediates thrombin-induced monocyte adhesion and endothelial permeability.Host derived biomarkers of inflammation, apoptosis, and endothelial activation are associated with clinical outcomes in patients with bacteremia and sepsis regardless of microbial etiology.Markers of endothelial function in migraine patients: Results from a bi-center prospective study.The role of bradykinin receptor type 2 for spontaneous extravasation in mice skin: Implications for non-allergic angio-oedema.Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.Tie2 protects the vasculature against thrombus formation in systemic inflammation.Ang-2 promotes lung cancer metastasis by increasing epithelial-mesenchymal transition.

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Angiopoietin-2 is critical for cytokine-induced vascular leakage

http://www.wikidata.org/entity/Q34935131

description

2013 nî lūn-bûn

@nan

2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Angiopoietin-2 is critical for cytokine-induced vascular leakage

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Angiopoietin-2 is critical for cytokine-induced vascular leakage

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Angiopoietin-2 is critical for cytokine-induced vascular leakage

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type

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Angiopoietin-2 is critical for cytokine-induced vascular leakage

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Angiopoietin-2 is critical for cytokine-induced vascular leakage

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Angiopoietin-2 is critical for cytokine-induced vascular leakage

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prefLabel

Angiopoietin-2 is critical for cytokine-induced vascular leakage

@ast

Angiopoietin-2 is critical for cytokine-induced vascular leakage

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Angiopoietin-2 is critical for cytokine-induced vascular leakage

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JOURNAL.PONE.0070459

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Angiopoietin-2 is critical for cytokine-induced vascular leakage

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Anna M Laib

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Elias K Loos

http://www.w3.org/2001/XMLSchema#string

Karoline Kruse

http://www.w3.org/2001/XMLSchema#string

Markus Thomas

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Ulrike Fiedler

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P2860

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

Angiopoietin-1 alters microvascular permeability coefficients in vivo via modification of endothelial glycocalyx

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation

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e70459

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scholarly article

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10.1371/JOURNAL.PONE.0070459

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8

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8

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Hellmut G Augustin

Andrew V Benest

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2013-08-05T00:00:00Z

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255791142

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23940579

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3734283

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