Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer - Wikidata - wikimedia - TriplyDB

Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer

Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer

http://www.wikidata.org/entity/Q34945422

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Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression Bone antiresorptive agents in the treatment of bone metastases associated with solid tumours or multiple myeloma Fracture Burden: What Two and a Half Decades of Dubbo Osteoporosis Epidemiology Study Data Reveal About Clinical Outcomes of Osteoporosis.Epithelial-mesenchymal transition in cancer metastasis through the lymphatic system.Addressing the controversy: do bisphosphonates directly affect primary tumors?HIF targets in bone remodeling and metastatic disease.Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models.Human stromal cells are required for an anti-breast cancer effect of zoledronic acid.Dual-therapy with αvβ3-targeted Sn2 lipase-labile fumagillin-prodrug nanoparticles and zoledronic acid in the Vx2 rabbit tumor model.Synthesis and evaluation of multivalent M2pep peptides for targeting alternatively activated M2 macrophages A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton.Effects of neoadjuvant chemotherapy with or without zoledronic acid on pathological response: A meta-analysis of randomised trials Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine.Zoledronic acid alters hematopoiesis and generates breast tumor-suppressive bone marrow cells.In Vivo Imaging Sheds Light on Immune Cell Migration and Function in Cancer.Animal models for breast cancer metastasis to bone: opportunities and limitations.Adoptive transfer of ex vivo expanded Vγ9Vδ2 T cells in combination with zoledronic acid inhibits cancer growth and limits osteolysis in a murine model of osteolytic breast cancer.Tumour-associated macrophages as treatment targets in oncology.Bisphosphonate-Functionalized Imaging Agents, Anti-Tumor Agents and Nanocarriers for Treatment of Bone Cancer.Role of tumour-associated macrophages in oral squamous cells carcinoma progression: an update on current knowledge.Progress in tumor-associated macrophage (TAM)-targeted therapeutics.Nanomedicine Strategies to Target Tumor-Associated Macrophages.Imaging of anticancer drug action in single cells.Zoledronic acid renders human M1 and M2 macrophages susceptible to Vδ2(+) γδ T cell cytotoxicity in a perforin-dependent manner.Repurposing Drugs in Oncology (ReDO)-nitroglycerin as an anti-cancer agent.Mouse models of metastasis: progress and prospects.Bone-Targeted Therapies in Cancer-Induced Bone Disease.Reverse Microemulsion-Based Synthesis of (Bis)phosphonate-Metal Materials with Controllable Physical Properties: An Example Using Zoledronic Acid-Calcium Complexes.Hallmarks of Bone Metastasis.Tumor Associated Macrophages as Therapeutic Targets for Breast Cancer.CD163-positive tumor-associated macrophages and CD8-positive cytotoxic lymphocytes are powerful diagnostic markers for the therapeutic stratification of osteosarcoma patients: An immunohistochemical analysis of the biopsies fromthe French OS2006 pha In vivo distribution of zoledronic acid in a bisphosphonate-metal complex-based nanoparticle formulation synthesized by a reverse microemulsion method.Macrophage Polarization in Chronic Inflammatory Diseases: Killers or Builders?Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways.Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy.Targeting Macrophages in Cancer: From Bench to Bedside.Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer.

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Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer

http://www.wikidata.org/entity/Q34945422

description

2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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Real-time intravital imaging e ...... isphosphonate action in cancer

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Real-time intravital imaging e ...... isphosphonate action in cancer

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Real-time intravital imaging e ...... isphosphonate action in cancer

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Cancer Discovery

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Real-time intravital imaging e ...... isphosphonate action in cancer

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Akira Nguyen

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Boris Kashemirov

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Charles E McKenna

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Jenny Down

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Nicholas Pocock

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Shuting Sun

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P2860

Microenvironmental regulation of metastasis

The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells

Oral bisphosphonate use and breast cancer incidence in postmenopausal women.

Endocrine therapy plus zoledronic acid in premenopausal breast cancer.

Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo

Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma

An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.

Bisphosphonates' antitumor activity: an unravelled side of a multifaceted drug class.

Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages.

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1

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25312016

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