Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
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Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitorsGelatinase B/MMP-9 in Tumour Pathogenesis and ProgressionMyeloid cell signatures in tumor microenvironment predicts therapeutic response in cancerMyeloid-Derived Suppressor Cells: Critical Cells Driving Immune Suppression in the Tumor MicroenvironmentThe impact of the myeloid response to radiation therapyDendritic cell vaccination, immune regulation, and clinical outcomes in ovarian cancerHampering immune suppressors: therapeutic targeting of myeloid-derived suppressor cells in cancerLow-intensity continuous ultrasound triggers effective bisphosphonate anticancer activity in breast cancer.Myeloid derived suppressor cells-An overview of combat strategies to increase immunotherapy efficacyMyeloid-derived suppressor cells as regulators of the immune systemBiochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decadeStat3 mediates myeloid cell-dependent tumor angiogenesis in miceMyeloid-derived cells are key targets of tumor immunotherapyTumor necrosis factor links chronic obstructive pulmonary disease and K-ras mutant lung cancer through induction of an immunosuppressive pro-tumor microenvironmentCoordinated regulation of myeloid cells by tumoursMacrophage depletion by free bisphosphonates and zoledronate-loaded red blood cellsMyeloid derived suppressor cells - a new therapeutic target in the treatment of cancer.Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.Microenvironment, oncoantigens, and antitumor vaccination: lessons learned from BALB-neuT mice.Chemotherapy and tumor microenvironment of pancreatic cancer.Dissecting the role of bone marrow stromal cells on bone metastases.Differential peripheral blood gene expression profile based on Her2 expression on primary tumors of breast cancer patients.Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma.Obesity, cholesterol metabolism, and breast cancer pathogenesisThe pre-metastatic niche: finding common ground.Anti-tumour activity of bisphosphonates in preclinical models of breast cancer.Tungsten targets the tumor microenvironment to enhance breast cancer metastasisReal-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancerLiposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells.Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasLGr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasisFluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivoCell-based immunotherapy with mesenchymal stem cells cures bisphosphonate-related osteonecrosis of the jaw-like disease in mice.Density of Gr1-positive myeloid precursor cells, p-STAT3 expression and gene expression pattern in canine mammary cancer metastasis.The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies.Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells.Molecular imaging of tumor-infiltrating macrophages in a preclinical mouse model of breast cancer.Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine.Tumour macrophages as potential targets of bisphosphonates.Roles of bone marrow cells in skeletal metastases: no longer bystanders
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Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Amino-biphosphonate-mediated M ...... e infiltration in tumor stroma
@en
Amino-biphosphonate-mediated M ...... infiltration in tumor stroma.
@nl
type
label
Amino-biphosphonate-mediated M ...... e infiltration in tumor stroma
@en
Amino-biphosphonate-mediated M ...... infiltration in tumor stroma.
@nl
prefLabel
Amino-biphosphonate-mediated M ...... e infiltration in tumor stroma
@en
Amino-biphosphonate-mediated M ...... infiltration in tumor stroma.
@nl
P2860
P50
P1433
P1476
Amino-biphosphonate-mediated M ...... e infiltration in tumor stroma
@en
P2093
Francesca M Barazzetta
P2860
P304
11438-11446
P356
10.1158/0008-5472.CAN-07-1882
P407
P577
2007-12-01T00:00:00Z