Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure. - Wikidata - wikimedia - TriplyDB

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure.

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure.

http://www.wikidata.org/entity/Q34978011

about

Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a.Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase Review of novel therapeutic targets for improving heart failure treatment based on experimental and clinical studies Cardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem Cells Gene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translation Model-specific selection of molecular targets for heart failure gene therapy Gene delivery technologies for cardiac applications 'Ryanopathy': causes and manifestations of RyR2 dysfunction in heart failure Gene therapy targets in heart failure: the path to translation Calcium-regulated transcriptional pathways in the normal and pathologic heart Characterization of regional left ventricular function in nonhuman primates using magnetic resonance imaging biomarkers: a test-retest repeatability and inter-subject variability study The fibrosis-cell death axis in heart failure Cardiac adenoviral S100A1 gene delivery rescues failing myocardium Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling Phosphorylation of the cAMP-dependent protein kinase (PKA) regulatory subunit modulates PKA-AKAP interaction, substrate phosphorylation, and calcium signaling in cardiac cells SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway Post-translational Modifications in Heart Failure: Small Changes, Big Impact Gene therapy delivery systems for enhancing viral and nonviral vectors for cardiac diseases: current concepts and future applications.Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy.Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a.Alpha1A-adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats.Heart failure management: the present and the future.Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload.Altered intracellular Ca2+ handling in heart failure.Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy Rescue of familial cardiomyopathies by modifications at the level of sarcomere and Ca2+ fluxes.Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding.Assessment of cardiovascular fibrosis using novel fluorescent probes.Meeting Koch's postulates for calcium signaling in cardiac hypertrophy.AFos dissociates cardiac myocyte hypertrophy and expression of the pathological gene program SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells.Decoding calcium signals involved in cardiac growth and function.Phospholamban and cardiac contractility.Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation Catheter-based antegrade intracoronary viral gene delivery with coronary venous blockade.Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy.Comparative analysis of parvalbumin and SERCA2a cardiac myocyte gene transfer in a large animal model of diastolic dysfunction.

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P2860

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure.

http://www.wikidata.org/entity/Q34978011

description

2000 nî lūn-bûn

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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2000年の論文

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Adenoviral gene transfer of SE ...... n transition to heart failure.

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P2860

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts

Generation of an adenovirus vector lacking E1, e2a, E3, and all of E4 except open reading frame 3.

Sarcoplasmic reticulum gene expression in cardiac hypertrophy and heart failure.

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

Modulation of ventricular function through gene transfer in vivo.

Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation.

Developmental and tissue-specific regulation of rabbit skeletal and cardiac muscle calcium channels involved in excitation-contraction coupling.

Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium

Phospholamban: a prominent regulator of myocardial contractility.

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