Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.
about
Nuclear receptors and epigenetic regulation: opportunities for nutritional targeting and disease preventionDirect methylation of FXR by Set7/9, a lysine methyltransferase, regulates the expression of FXR target genesIdentification of a functional antioxidant response element within the eighth intron of the human ABCC3 geneA Review of the Scaffold Protein Menin and its Role in Hepatobiliary Pathology.Clinical application of transcriptional activators of bile salt transporters.Bile formation and secretion.Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.Requirement for MLL3 in p53 regulation of hepatic expression of small heterodimer partner and bile acid homeostasis.Farnesoid X receptor-induced lysine-specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicityElevated copper impairs hepatic nuclear receptor function in Wilson's disease.Loss of Mll3 Catalytic Function Promotes Aberrant MyelopoiesisX-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific mannerGlobal identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathwaysThe solute carrier family 10 (SLC10): beyond bile acid transportNuclear factor-κB regulates the expression of multiple genes encoding liver transport proteins.SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes.Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genesSIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.Epigenomic regulation of bile acid metabolism: emerging role of transcriptional cofactors.A shift in paradigm towards human biology-based systems for cholestatic-liver diseases.Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by Rifampicin.Role of farnesoid X receptor in cholestasis.FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.Epigenetic Regulation of Hepatitis B Virus Covalently Closed Circular DNA: Implications for Epigenetic Therapy against Chronic Hepatitis B.Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk.Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.
P2860
Q26849574-3252EDEA-D8CF-4868-AA5A-A46E61A1BED1Q28115198-EA67A8D0-4219-4F56-8EEE-28271212B74DQ28250453-BD11463D-3A91-40CC-90F7-AABF7DCEEF5EQ30401808-05003647-D5E1-427F-BDAA-CDDABAFEFE60Q33709930-98B95198-4121-4826-BCB3-46DB481664DCQ33881922-CD91FDB8-4D6A-4E90-B7B4-A0060BEE3601Q34444945-A7452226-2667-4362-8D42-9F98ED4F25B4Q35595716-8270627D-0C4F-45F3-B5CA-F5CF571496B4Q35779630-ED4E64C3-1DD5-451E-A205-34C8C4FC9D8FQ36106015-B1E153DC-7656-4EB5-9B64-807B2F0C0703Q36127733-7BEA9A3E-0C78-444F-81D9-4F7742FBAF10Q36167570-868B5065-FC99-4EF6-B15E-982EF65E129AQ36378382-A2B11CB2-EF2D-4649-A10A-A59FC6E65201Q36700386-3CA07D43-FD92-42DF-8205-483F2066F761Q36811310-98032D0C-2EA4-4A58-B494-C4D2B36FA2FBQ36832721-7B1776B5-C15A-45B2-82B4-CE013F7FF5D6Q37095431-920D34E9-CB17-4240-9B1A-0E7C2E3059CDQ37722381-6347BE4B-1DAA-4136-B4AB-FE607A7944E9Q38009566-A3578990-BDE1-4F54-AB4D-9DA1954DFDB0Q38595049-C2FB8835-8737-4A3B-9770-1E04B3FBA9A9Q38702217-BE49FED8-1CD3-47CA-9F04-8DADC3444A6CQ38887864-0349B0CD-6A50-47EC-94B4-764C3FD6A04EQ39674360-C6D402DD-E59B-4787-9AAF-EE83F3899666Q40073818-0401DC37-FF27-4A2B-8239-15CAE1E24584Q41985591-E95B0B64-F6C1-4ECC-BED0-218D164C9320Q52369540-19269150-848F-4BD4-961A-22B253F7D8C3
P2860
Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@ast
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@en
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@nl
type
label
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@ast
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@en
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@nl
prefLabel
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@ast
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@en
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@nl
P2093
P2860
P356
P1476
Histone H3K4 trimethylation by ...... downregulated in cholestasis.
@en
P2093
Frederick J Suchy
J A Goldstein
Jaeyong Ahn
M Ananthanarayanan
N Balasubramaniyan
S Surapureddi
Yanfeng Li
P2860
P304
P356
10.1152/AJPGI.00499.2010
P577
2011-02-17T00:00:00Z